Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | LDHA | P00338 | 2/20 | 0.40 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.40 |
| ▸ | KMO | O15229 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27582587 | 0.83 | FAAH (0.43) | FAAHADORA3ADORA1ALDH1A1NPC1 | |
| SCHEMBL29123709 | 0.83 | FAAH (0.42) | FAAHADORA1ALDH1A1NPC1RAB9A | |
| SCHEMBL6028454 | 0.80 | ALDH1A1 (0.45) | FAAHADORA3ADORA1ALDH1A1NPC1 | |
| SCHEMBL27577380 | 0.77 | RAB9A (0.47) | ADORA1ALDH1A1NPC1RAB9AHPGD | |
| SCHEMBL10645106 | 0.75 | FAAH (0.56) | FAAHADORA3ADORA1ALDH1A1NPC1 | |
| SCHEMBL27831341 | 0.74 | RECQL (0.42) | FAAHADORA3ADORA1ALDH1A1NPC1 | |
| SCHEMBL21929949 | 0.73 | MAPK1 (0.48) | ALDH1A1RAB9ASMN1; SMN2GAAPOLB | |
| SCHEMBL28630919 | 0.72 | ALDH1A1 (0.36) | ALDH1A1GAA | |
| SCHEMBL28402434 | 0.71 | OGT (0.46) | NPC1RAB9A | |
| SCHEMBL11552222 | 0.70 | BACE1 (0.42) | ADORA3ADORA1ALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1363925-B8 | MACROLIDE ANTIBIOTICS | GLAXO GROUP LTD (GB) | 2007-04-25 | — | — | EP | disclosed |
| EP-1363925-A1 | MACROLIDE ANTIBIOTICS | GLAXO GROUP LIMITED (GB) | 2003-11-26 | — | — | EP | disclosed |
| WO-2002050091-A1 | MACROLIDE ANTIBIOTICS | GLAXO GROUP LIMITED (GB) | 2002-06-27 | — | — | WO | disclosed |