Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.43 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14946949 | 0.73 | MAPT (0.53) | RAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL5209449 | 0.73 | FAAH (0.43) | POLBRAB9ASMN1; SMN2ALDH1A1GAA | |
| SCHEMBL29123709 | 0.72 | FAAH (0.42) | RAB9AALDH1A1 | |
| SCHEMBL14946928 | 0.71 | SMN1; SMN2 (0.48) | RAB9ASMN1; SMN2MAPTALDH1A1GAA | |
| SCHEMBL17673651 | 0.71 | RAB9A (0.53) | MAPK1POLBRAB9ASMN1; SMN2MAPT | |
| SCHEMBL254774 | 0.69 | CES1 (0.70) | MAPK1POLBRAB9AMAPTCES2 | |
| SCHEMBL27499697 | 0.69 | CES1 (0.70) | MAPK1POLBRAB9ACES2CES1 | |
| 4-Nitrobenzoic Acid SCHEMBL17460232 | 0.68 | TDP1 (0.55) | MAPK1POLBMAPTCES2CES1 | |
| SCHEMBL16335594 | 0.68 | PKM (0.68) | MAPK1POLBRAB9ASMN1; SMN2MAPT | |
| SCHEMBL28489642 | 0.68 | MEN1 (0.60) | MAPK1POLBRAB9ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200148696-A1 | Urea/Carbamates FAAH MAGL Or Dual FAAH/MAGL Inhibitors And Uses Thereof | NORTHEASTERN UNIVERSITY | 2020-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200148696-A1 | Urea/Carbamates FAAH MAGL Or Dual FAAH/MAGL Inhibitors And Uses Thereof | FAAH, MGLL, FAAH2 | MAPK1 3385/4885POLB 2889/4885RAB9A 1087/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.