Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 4/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5628892 | 0.78 | ADRA2C (0.35) | F2ADRA2CF10ACHE | |
| Trifluoroacetic Acid SCHEMBL5206988 | 0.75 | FOLH1 (0.35) | F2PRSS1PRSS2PRSS3FOLH1 | |
| Trifluoroacetic Acid SCHEMBL5209569 | 0.74 | F2 (0.31) | F2FOLH1 | |
| Trifluoroacetic Acid SCHEMBL5212475 | 0.74 | GAA (0.37) | F2PRSS1PRSS2PRSS3FOLH1 | |
| Trifluoroacetic Acid SCHEMBL5629214 | 0.73 | F2 (0.32) | F2PRSS1PRSS2PRSS3FOLH1 | |
| SCHEMBL5210877 | 0.73 | ADRA2C (0.52) | F2ADRA2CACHE | |
| Trifluoroacetic Acid SCHEMBL5210467 | 0.72 | F2 (0.37) | F2PRSS1PRSS2PRSS3FOLH1 | |
| Trifluoroacetic Acid SCHEMBL5203647 | 0.72 | F2 (0.36) | F2PRSS1PRSS2PRSS3FOLH1 | |
| Trifluoroacetic Acid SCHEMBL5210906 | 0.72 | ACHE (0.39) | F2PRSS1PRSS2PRSS3ADRA2C | |
| Trifluoroacetic Acid SCHEMBL5213937 | 0.72 | F2 (0.34) | F2PRSS1PRSS2PRSS3FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1343561-B1 | SERINE PROTEASE INHIBITORS | TULARIK LTD (GB) | 2007-02-28 | — | — | EP | disclosed |
| EP-1343561-A1 | SERINE PROTEASE INHIBITORS | Tularik Limited (GB) | 2003-09-17 | — | — | EP | disclosed |
| WO-2002047762-A1 | SERINE PROTEASE INHIBITORS | TULARIK LIMITED (GB) | 2002-06-20 | — | — | WO | disclosed |