Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL5209569

NC(=O)C1NC2C=CC=CC2S1.NCc1cccc(C(=O)N(CC(=O)O)c2ccccc2C(F)(F)F)c1.O=C(O)C(F)(F)F

nearest known ligand 0.31

Full drug profile on Sugi Atlas →

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
F2 P00734 2/20 0.31
FOLH1 Q04609 2/20 0.30
MRGPRX4 Q96LA9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5628892 0.85 ADRA2C (0.35) F2
Trifluoroacetic Acid SCHEMBL6993585 0.84
Trifluoroacetic Acid SCHEMBL5204098 0.83
Trifluoroacetic Acid SCHEMBL5210666 0.81 OPRM1 (0.31) F2
Trifluoroacetic Acid SCHEMBL5212701 0.81 LOXL2 (0.31) F2FOLH1
SCHEMBL5208096 0.77 KMT2A (0.36)
SCHEMBL5205927 0.75 LOXL2 (0.34) F2
Trifluoroacetic Acid SCHEMBL5208897 0.74 F2 (0.37) F2MRGPRX4
Trifluoroacetic Acid SCHEMBL5209705 0.74 F2 (0.33) F2FOLH1
Trifluoroacetic Acid SCHEMBL5206988 0.73 FOLH1 (0.35) F2FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1343561-B1 SERINE PROTEASE INHIBITORS TULARIK LTD (GB) 2007-02-28 EP disclosed