Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | GAA | P10253 | 4/20 | 0.37 |
| ▸ | CNR2 | P34972 | 4/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TLR2 | O60603 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5211197 | 0.93 | FLT3 (0.36) | MAPTALDH1A1GAATP53NPSR1 | |
| Trifluoroacetic Acid SCHEMBL5207793 | 0.90 | PDE4D (0.40) | PDE4DMAPTALDH1A1GAACNR2 | |
| Trifluoroacetic Acid SCHEMBL5207834 | 0.90 | PDE4D (0.41) | PDE4DMAPTALDH1A1GAACNR2 | |
| Trifluoroacetic Acid SCHEMBL4809946 | 0.90 | PDE4D (0.36) | PDE4DMAPTALDH1A1GAACNR2 | |
| Trifluoroacetic Acid SCHEMBL5211226 | 0.89 | PDE4D (0.37) | PDE4DMAPTALDH1A1GAACNR2 | |
| Trifluoroacetic Acid SCHEMBL5205966 | 0.87 | PDE4D (0.39) | PDE4DMAPTALDH1A1GAACNR2 | |
| Trifluoroacetic Acid SCHEMBL5208796 | 0.86 | SMN1; SMN2 (0.35) | MAPTALDH1A1GAAADORA3ADORA2A | |
| Trifluoroacetic Acid SCHEMBL5208294 | 0.86 | MEN1 (0.31) | NPSR1 | |
| Trifluoroacetic Acid SCHEMBL5209196 | 0.86 | IKBKB (0.33) | GAANPSR1 | |
| Trifluoroacetic Acid SCHEMBL5280152 | 0.83 | ALDH1A1 (0.40) | MAPTALDH1A1CNR2TP53KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1343561-B1 | SERINE PROTEASE INHIBITORS | TULARIK LTD (GB) | 2007-02-28 | — | — | EP | disclosed |