Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
| ▸ | FLT3 | P36888 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5211197 | 0.90 | FLT3 (0.36) | MEN1POLBKMT2ANPSR1RORC | |
| Trifluoroacetic Acid SCHEMBL5209056 | 0.89 | F2 (0.34) | MEN1POLBKMT2ANPSR1RORC | |
| Trifluoroacetic Acid SCHEMBL5208796 | 0.88 | SMN1; SMN2 (0.35) | MEN1POLBKMT2A | |
| Trifluoroacetic Acid SCHEMBL5209115 | 0.88 | ENPP2 (0.34) | OPRM1OPRD1 | |
| Trifluoroacetic Acid SCHEMBL5209196 | 0.87 | IKBKB (0.33) | NPSR1RORCFLT3 | |
| Trifluoroacetic Acid SCHEMBL5209741 | 0.86 | PDE4D (0.38) | NPSR1 | |
| Trifluoroacetic Acid SCHEMBL5209006 | 0.85 | PIK3CA (0.33) | MEN1POLBKMT2ANPSR1OPRM1 | |
| Trifluoroacetic Acid SCHEMBL5208291 | 0.83 | MAPT (0.33) | — | |
| Trifluoroacetic Acid SCHEMBL5206929 | 0.78 | NPSR1 (0.34) | MEN1POLBKMT2ANPSR1RORC | |
| Trifluoroacetic Acid SCHEMBL5209718 | 0.77 | FLT3 (0.39) | MEN1POLBKMT2ANPSR1RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1343561-B1 | SERINE PROTEASE INHIBITORS | TULARIK LTD (GB) | 2007-02-28 | — | — | EP | disclosed |