Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | FABP4 | P15090 | 1/20 | 0.32 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 2/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.31 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.31 |
| ▸ | FLT1 | P17948 | 1/20 | 0.31 |
| ▸ | FLT4 | P35916 | 1/20 | 0.31 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.30 |
| ▸ | KLK1 | P06870 | 1/20 | 0.30 |
| ▸ | FLT3 | P36888 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5211197 | 0.90 | FLT3 (0.36) | FLT3GAANPSR1RORC | |
| Trifluoroacetic Acid SCHEMBL5204258 | 0.90 | F10 (0.34) | F10FABP4FABP5F2PARP1 | |
| Trifluoroacetic Acid SCHEMBL5206308 | 0.88 | MEN1 (0.31) | F10FABP4FABP5MAPK14PARP1 | |
| Trifluoroacetic Acid SCHEMBL5208796 | 0.87 | SMN1; SMN2 (0.35) | TSHRGAAHTT | |
| Trifluoroacetic Acid SCHEMBL5208294 | 0.87 | MEN1 (0.31) | FLT3NPSR1RORC | |
| Trifluoroacetic Acid SCHEMBL5204591 | 0.86 | F10 (0.33) | F10F2PARP1FLT3 | |
| Trifluoroacetic Acid SCHEMBL5209741 | 0.86 | PDE4D (0.38) | GAANPSR1 | |
| SCHEMBL5209500 | 0.83 | ENPP2 (0.36) | IKBKBF2TSHRPARP1KLKB1 | |
| Trifluoroacetic Acid SCHEMBL5208291 | 0.82 | MAPT (0.33) | F2 | |
| Trifluoroacetic Acid SCHEMBL5209718 | 0.78 | FLT3 (0.39) | FLT3GAANPSR1RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1343561-B1 | SERINE PROTEASE INHIBITORS | TULARIK LTD (GB) | 2007-02-28 | — | — | EP | disclosed |