Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.44 |
| ▸ | PPARG | P37231 | 17/20 | 0.44 |
| ▸ | PPARA | Q07869 | 13/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5210830 | 0.92 | MAPT (0.43) | HRH3 | |
| SCHEMBL2523393 | 0.89 | HRH3 (0.48) | HRH3PPARGPPARA | |
| SCHEMBL2523398 | 0.89 | HRH3 (0.48) | HRH3PPARGPPARA | |
| SCHEMBL5211136 | 0.89 | PPARG (0.56) | PPARGPPARA | |
| SCHEMBL5207399 | 0.85 | PPARA (0.42) | PPARGPPARA | |
| SCHEMBL5210317 | 0.84 | FFAR1 (0.52) | PPARGPPARA | |
| SCHEMBL5210810 | 0.83 | PPARG (0.57) | PPARGPPARA | |
| SCHEMBL5205913 | 0.83 | FFAR1 (0.50) | PPARGPPARA | |
| SCHEMBL5206559 | 0.83 | MAPT (0.46) | PPARGPPARA | |
| SCHEMBL5210696 | 0.83 | PPARG (0.51) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1448523-B1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE | NOVARTIS AG (CH) | 2007-08-22 | — | — | EP | claimed |