Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MPO | P05164 | 1/20 | 0.35 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TEK | Q02763 | 3/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | GCGR | P47871 | 3/20 | 0.30 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.30 |
| ▸ | CMA1 | P23946 | 1/20 | 0.30 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.30 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.30 |
| ▸ | GIPR | P48546 | 1/20 | 0.30 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5217315 | 0.90 | PIK3CD (0.43) | PIK3CDPKMMPOCYSLTR1MEN1 | |
| SCHEMBL5215860 | 0.83 | PIK3CD (0.44) | PIK3CDPKMMPOCYSLTR1KDM1A | |
| SCHEMBL5215051 | 0.82 | PIK3CD (0.43) | PIK3CDPKMMPOCYSLTR1GCGR | |
| SCHEMBL5212891 | 0.81 | PIK3CD (0.47) | PIK3CDPKMMPOCYSLTR1MEN1 | |
| SCHEMBL5217976 | 0.81 | GCGR (0.37) | PIK3CDPKMMPOCYSLTR1KDM1A | |
| SCHEMBL5215059 | 0.78 | MPO (0.46) | PIK3CDPKMMPOCYSLTR1 | |
| SCHEMBL5212507 | 0.78 | PIK3CD (0.43) | PIK3CDPKMMPOCYSLTR1MEN1 | |
| SCHEMBL5218139 | 0.78 | PIK3CD (0.43) | PIK3CDPKMMPOCYSLTR1KDR | |
| SCHEMBL5211464 | 0.77 | PIK3CD (0.42) | PIK3CDPKMMPOCYSLTR1GCGR | |
| SCHEMBL4773675 | 0.76 | DYRK1A (0.37) | PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1636213-B1 | 3-ARYLOXY AND 3-HETEROARYLOXY SUBSTITUTED BENZO(B) THIOPHENES AS THERAPEUTIC AGENTS WITH PI3K ACTIVITY | WARNER LAMBERT CO (US) | 2007-06-13 | — | — | EP | claimed |