Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.44 |
| ▸ | MPO | P05164 | 1/20 | 0.39 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.39 |
| ▸ | ITK | Q08881 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 2/20 | 0.32 |
| ▸ | IL2 | P60568 | 1/20 | 0.31 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.31 |
| ▸ | GCGR | P47871 | 1/20 | 0.31 |
| ▸ | CCNC | P24863 | 1/20 | 0.30 |
| ▸ | CDK8 | P49336 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5215051 | 0.91 | PIK3CD (0.43) | PIK3CDMPOCYSLTR1ITKPKM | |
| SCHEMBL4942765 | 0.88 | PIK3CD (0.54) | PIK3CDMPOCYSLTR1ITKPKM | |
| SCHEMBL5212891 | 0.86 | PIK3CD (0.47) | PIK3CDMPOCYSLTR1ITKPKM | |
| SCHEMBL5212507 | 0.85 | PIK3CD (0.43) | PIK3CDMPOCYSLTR1PKMCCNC | |
| SCHEMBL5218139 | 0.85 | PIK3CD (0.43) | PIK3CDMPOCYSLTR1PKMCCNC | |
| SCHEMBL5215059 | 0.84 | MPO (0.46) | PIK3CDMPOCYSLTR1PKMCCNC | |
| SCHEMBL5211464 | 0.84 | PIK3CD (0.42) | PIK3CDMPOCYSLTR1PKMGCGR | |
| SCHEMBL5217976 | 0.83 | GCGR (0.37) | PIK3CDMPOCYSLTR1ITKPKM | |
| SCHEMBL5212435 | 0.83 | PIK3CD (0.42) | PIK3CDMPOCYSLTR1PKMGCGR | |
| SCHEMBL5211776 | 0.83 | PIK3CD (0.45) | PIK3CDMPOCYSLTR1PKMKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1636213-B1 | 3-ARYLOXY AND 3-HETEROARYLOXY SUBSTITUTED BENZO(B) THIOPHENES AS THERAPEUTIC AGENTS WITH PI3K ACTIVITY | WARNER LAMBERT CO (US) | 2007-06-13 | — | — | EP | claimed |