Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.54 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | APP | P05067 | 1/20 | 0.53 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.53 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.53 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.53 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ANPEP | P15144 | 1/20 | 0.49 |
| ▸ | TBXAS1 | P24557 | 7/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | KMO | O15229 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.47 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Niacin SCHEMBL27947451 | 0.89 | GAA (0.70) | MKNK1MKNK2GAAALDH1A1APP | |
| SCHEMBL8996251 | 0.83 | TBXAS1 (0.58) | MKNK1MKNK2GAAALDH1A1APP | |
| SCHEMBL11067952 | 0.83 | TBXAS1 (0.67) | MKNK1MKNK2GAAALDH1A1APP | |
| Picolamine SCHEMBL27476690 | 0.83 | NAPRT (0.59) | NAPRTCYP2A6KDM4ETBXAS1RECQL | |
| Hydrochloric Acid SCHEMBL11062270 | 0.82 | TBXAS1 (0.68) | MKNK1MKNK2GAAALDH1A1APP | |
| Picolamine SCHEMBL28291842 | 0.81 | NAPRT (0.56) | NAPRTCYP2A6KDM4ETBXAS1RECQL | |
| SCHEMBL5353235 | 0.81 | TBXAS1 (0.62) | MKNK1MKNK2GAAALDH1A1APP | |
| Terephthalic Acid SCHEMBL31728635 | 0.80 | LOXL2 (0.64) | ALDH1A1NAPRTCYP1A2CYP2C9LOXL2 | |
| Picolamine SCHEMBL17850 | 0.80 | — | — | |
| Aminomethylbenzoic Acid SCHEMBL38758 | 0.80 | ALDH1A1 (0.60) | GAAALDH1A1KDM4EANPEPRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1362033-B1 | PYRIDINE MATRIX METALLOPROTEINASE INHIBITORS | WARNER LAMBERT CO (US) | 2007-04-04 | — | — | EP | claimed |