SCHEMBL1475280

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1477702	0.84	KCNH2 (0.42)	CHRM2CHRM1CHRM3CHRM4KCNH2
	SCHEMBL1475162	0.80	CHRM4 (0.41)	CHRM2CHRM1CHRM3CHRM4KCNH2
	SCHEMBL1477211	0.79	MAOA (0.51)	ACHEDRD2DRD4DRD3ATM
	SCHEMBL1476133	0.79	ACHE (0.42)	ACHEBCHEDRD2DRD4DRD3
	SCHEMBL1475948	0.76	FAAH (0.42)	CHRM2CHRM1CHRM3ACHEBCHE
	SCHEMBL1475625	0.74	MAOA (0.47)	ACHEDRD2DRD4DRD3ATM
	Oxalic Acid SCHEMBL1475606	0.73	FAAH (0.44)	CHRM2CHRM1CHRM3ACHEBCHE
	SCHEMBL1475235	0.72	ACHE (0.36)	ACHEBCHEDRD2DRD4DRD3
	SCHEMBL12748675	0.72	KCNH2 (0.47)	KCNH2ACHEDRD4
	SCHEMBL5212084	0.71	SCD (0.43)	CHRM2CHRM1CHRM3CHRM4DRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.