Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.48 |
| ▸ | DAO | P14920 | 1/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | MET | P08581 | 4/20 | 0.44 |
| ▸ | CHKA | P35790 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27681462 | 0.98 | ALDH1A1 (0.49) | ALDH1A1MAPTKDM4ETP53HSP90AA1 | |
| SCHEMBL29673226 | 0.78 | ALDH1A1 (0.58) | ALDH1A1MAPTKDM4ETP53HSP90AA1 | |
| SCHEMBL507149 | 0.78 | ALDH1A1 (0.58) | ALDH1A1MAPTKDM4ETP53HSP90AA1 | |
| SCHEMBL2107923 | 0.78 | NPC1 (0.57) | ALDH1A1MAPTKDM4ETP53HSP90AA1 | |
| SCHEMBL30586439 | 0.78 | ALDH1A1 (0.58) | ALDH1A1MAPTKDM4ETP53HSP90AA1 | |
| Iodide SCHEMBL20524052 | 0.76 | ALDH1A1 (0.56) | ALDH1A1MAPTKDM4ETP53HSP90AA1 | |
| SCHEMBL1764709 | 0.75 | CA1 (0.57) | CA1CA2CA5ACA9 | |
| SCHEMBL6383861 | 0.75 | CA2 (0.37) | METCA1CA2CA5ACA9 | |
| SCHEMBL6961498 | 0.75 | DAO (0.57) | ALDH1A1MAPTKDM4ETP53HSP90AA1 | |
| SCHEMBL2597877 | 0.75 | ALDH1A1 (0.59) | ALDH1A1MAPTKDM4ETP53HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101039931-A | Novel product, method and intermediates for the preparation of azetidine derivatives | AVENTIS PHARMA SA (FR) | 2007-09-19 | — | — | CN | disclosed |
| EP-1805167-A2 | NOVEL PRODUCT, METHOD AND INTERMEDIATES FOR THE PREPARATION OF AZETIDINE DERIVATIVES | Aventis Pharma S.A. (FR) | 2007-07-11 | — | — | EP | disclosed |
| WO-2006040465-A2 | NOVEL PRODUCT, METHOD AND INTERMEDIATES FOR THE PREPARATION OF AZETIDINE DERIVATIVES | AVENTIS PHARMA S.A. (FR) | 2006-04-20 | — | — | WO | disclosed |