Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5190665 | 0.92 | KMT2A (0.51) | KMT2AMEN1EPHX1ALDH1A1POLB | |
| SCHEMBL5193468 | 0.85 | ALDH1A1 (0.52) | KMT2AMEN1ALDH1A1HTTLMNA | |
| SCHEMBL5190763 | 0.85 | RXFP1 (0.46) | KMT2AMEN1EPHX1ALDH1A1POLB | |
| SCHEMBL5193934 | 0.81 | ALDH1A1 (0.53) | KMT2AMEN1ALDH1A1HTTLMNA | |
| SCHEMBL5193560 | 0.81 | CCR2 (0.48) | KMT2AMEN1ALDH1A1LMNATSHR | |
| SCHEMBL5191195 | 0.80 | MEN1 (0.59) | KMT2AMEN1EPHX1ALDH1A1APOBEC3A | |
| SCHEMBL5193499 | 0.80 | FAAH (0.52) | KMT2AMEN1ALDH1A1HTTGAA | |
| SCHEMBL5206456 | 0.77 | MAPK1 (0.58) | KMT2AMEN1ALDH1A1POLBHTT | |
| SCHEMBL5193950 | 0.77 | CCR2 (0.46) | KMT2AMEN1 | |
| SCHEMBL5195658 | 0.76 | ALDH1A1 (0.44) | KMT2AMEN1ALDH1A1HTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0968206-B8 | N-HETEROCYCLIC DERIVATIVES AS NOS INHIBITORS | BERLEX INC (US) | 2007-01-24 | — | — | EP | claimed |
| EP-0968206-A1 | N-HETEROCYCLIC DERIVATIVES AS NOS INHIBITORS | BERLEX LABORATORIES, INC. (US) | 2000-01-05 | — | — | EP | claimed |
| WO-1998037079-A1 | N-HETEROCYCLIC DERIVATIVES AS NOS INHIBITORS | BERLEX LABORATORIES, INC. (US) | 1998-08-27 | — | — | WO | claimed |