Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | PDE5A | O76074 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5190665 | 0.92 | KMT2A (0.51) | RXFP1GAAHPGDLMNAALDH1A1 | |
| SCHEMBL5192873 | 0.86 | LMNA (0.47) | PDE5AGAALMNAKMT2AMEN1 | |
| SCHEMBL5191071 | 0.86 | LMNA (0.47) | PDE5AGAALMNAKMT2AMEN1 | |
| SCHEMBL5278574 | 0.85 | LMNA (0.48) | PDE5AGAALMNA | |
| SCHEMBL5213606 | 0.85 | KMT2A (0.60) | GAALMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL5193999 | 0.81 | ALDH1A1 (0.46) | GAAHPGDLMNAALDH1A1POLB | |
| SCHEMBL5193168 | 0.79 | RAB9A (0.47) | GAALMNAALDH1A1KMT2APOLB | |
| SCHEMBL5207369 | 0.77 | GAA (0.42) | PDE5AGAALMNAALDH1A1KMT2A | |
| SCHEMBL5190702 | 0.75 | GAA (0.49) | GAALMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL5195267 | 0.74 | ALDH1A1 (0.41) | GAALMNAALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0968206-B8 | N-HETEROCYCLIC DERIVATIVES AS NOS INHIBITORS | BERLEX INC (US) | 2007-01-24 | — | — | EP | disclosed |
| EP-0968206-A1 | N-HETEROCYCLIC DERIVATIVES AS NOS INHIBITORS | BERLEX LABORATORIES, INC. (US) | 2000-01-05 | — | — | EP | disclosed |
| WO-1998037079-A1 | N-HETEROCYCLIC DERIVATIVES AS NOS INHIBITORS | BERLEX LABORATORIES, INC. (US) | 1998-08-27 | — | — | WO | disclosed |