Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.54 |
| ▸ | NAMPT | P43490 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.52 |
| ▸ | BRAF | P15056 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5215208 | 0.86 | RAB9A (0.60) | TDP1NAMPTCYP1A2CYP3A4SMN1; SMN2 | |
| SCHEMBL5218284 | 0.85 | KCNK3 (0.58) | KCNK3NAMPTCYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL259177 | 0.85 | TDP1 (0.78) | TDP1TSHRKCNK3NAMPTCYP1A2 | |
| SCHEMBL5215050 | 0.83 | KMT2A (0.59) | TDP1TSHRNAMPTCYP1A2CYP2C9 | |
| SCHEMBL9192069 | 0.79 | KMT2A (0.72) | CYP1A2SMN1; SMN2PKMKMT2AHTT | |
| SCHEMBL14415899 | 0.79 | THRB (0.77) | TSHRCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL5216570 | 0.78 | ALDH1A1 (0.61) | NAMPTCYP1A2CYP3A4CYP2C19SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9187992 | 0.78 | KMT2A (0.70) | CYP1A2SMN1; SMN2PKMKMT2AHTT | |
| SCHEMBL9435155 | 0.77 | TDP1 (0.62) | TDP1TSHRKCNK3CYP1A2CYP3A4 | |
| SCHEMBL14724809 | 0.76 | NPC1 (0.72) | TSHRNAMPTSMN1; SMN2KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1198456-B1 | POTASSIUM CHANNEL OPENERS | ABBOTT LAB (US) | 2007-09-19 | — | — | EP | claimed |
| EP-1198456-B1 | POTASSIUM CHANNEL OPENERS | ABBOTT LAB (US) | 2007-09-19 | — | — | EP | disclosed |