Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MC4R | P32245 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4496754 | 0.75 | LTA4H (0.44) | ALDH1A1KDM4E | |
| SCHEMBL7276585 | 0.72 | — | — | |
| SCHEMBL467600 | 0.68 | MC4R (0.43) | ALDH1A1KDM4EMAPTMC4RLMNA | |
| SCHEMBL3572933 | 0.66 | ALDH1A1 (0.43) | ALDH1A1KDM4EMAPTRECQLHTT | |
| SCHEMBL18713223 | 0.65 | HTT (0.37) | ALDH1A1KDM4EMAPTRECQLHTT | |
| SCHEMBL188649 | 0.65 | HRH3 (0.40) | KDM4E | |
| SCHEMBL2476193 | 0.62 | PIK3CA (0.34) | — | |
| SCHEMBL5253017 | 0.62 | PSMB1 (0.45) | — | |
| SCHEMBL468785 | 0.61 | ADRA2C (0.34) | ALDH1A1KDM4EMAPT | |
| SCHEMBL5108436 | 0.61 | PSMB1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778632-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2007-05-02 | — | — | EP | disclosed |
| WO-2005123673-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2005-12-29 | — | — | WO | disclosed |