Known targets — ChEMBL curated mechanism
GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQ
The experimentally established mechanism targets of Methyl Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.81 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.81 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.48 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.48 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALPG | P10696 | 1/20 | 0.39 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methyl Alcohol SCHEMBL5528692 | 0.97 | TDP1 (0.85) | TDP1KDM4EALDH1A1CHRNB2CHRNA4 | |
| Methyl Alcohol SCHEMBL27263369 | 0.95 | TDP1 (0.90) | TDP1KDM4EALDH1A1CHRNB2CHRNA4 | |
| Water SCHEMBL6859264 | 0.95 | ALDH1A1 (0.90) | TDP1KDM4EALDH1A1CHRNB2CHRNA4 | |
| Water SCHEMBL3139 | 0.95 | ALDH1A1 (0.90) | TDP1KDM4EALDH1A1CHRNB2CHRNA4 | |
| Water SCHEMBL6859263 | 0.92 | KDM4E (0.85) | TDP1KDM4EALDH1A1CHRNB2CHRNA4 | |
| Water SCHEMBL6841853 | 0.92 | ALDH1A1 (0.85) | TDP1KDM4EALDH1A1CHRNB2CHRNA4 | |
| Water SCHEMBL11243425 | 0.92 | KDM4E (0.85) | TDP1KDM4EALDH1A1CHRNB2CHRNA4 | |
| Ammonia Solution, Strong SCHEMBL27549344 | 0.92 | ALDH1A1 (0.85) | TDP1KDM4EALDH1A1CHRNB2CHRNA4 | |
| Water SCHEMBL11251666 | 0.92 | KDM4E (0.85) | TDP1KDM4EALDH1A1CHRNB2CHRNA4 | |
| Water SCHEMBL27674361 | 0.92 | ALDH1A1 (0.85) | TDP1KDM4EALDH1A1CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117117328-B | Electrolyte and lithium ion battery containing same | 深圳华驰新能源科技有限公司 | 2024-01-12 | — | — | CN | claimed |
| CN-117117328-A | Electrolyte and lithium ion battery containing same | 深圳华驰新能源科技有限公司 | 2023-11-24 | — | — | CN | claimed |
| CN-114394826-B | Manufacturing process of high-performance nano-material ceramic thin-film device | 湖南湘瓷科艺有限公司 | 2022-10-14 | — | — | CN | claimed |
| CN-114479131-A | High-toughness PP (polypropylene) particles and preparation method thereof | 安徽冠泓塑业有限公司 | 2022-05-13 | — | — | CN | claimed |
| CN-114394826-A | Manufacturing process of high-performance nano-material ceramic thin-film device | 湖南湘瓷科艺有限公司 | 2022-04-26 | — | — | CN | claimed |
| CN-114196457-A | High-thermal-conductivity lubricating oil and production process thereof | 苏庆龙 | 2022-03-18 | — | — | CN | claimed |
| CN-104448830-B | A kind of phosphorus silicon composite flame-retardant agent and its preparation method and application | 上海工程技术大学 | 2017-04-05 | — | — | CN | claimed |
| CN-1314777-C | Fluoro liquid crystal compound for thin film transistor liquid crystal display device and its preparing method | LI ZHENHAI (CN) | 2007-05-09 | — | — | CN | claimed |
| CN-1710019-A | Fluoro liquid crystal compound for thin film transistor liquid crystal display device and its preparing method | LI ZHENHAI (CN) | 2005-12-21 | — | — | CN | claimed |
| WO-2024141052-A1 | ESTROGEN-RECEPTOR MODULATOR AND USE THEREOF | 江苏威凯尔医药科技有限公司 | 2024-07-04 | — | — | WO | disclosed |
| CN-118271284-A | Estrogen receptor modulators and uses thereof | 江苏威凯尔医药科技有限公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-118201930-A | WEE1 protein kinase degradation agent and application thereof | 杭州格博生物医药有限公司 | 2024-06-14 | — | — | CN | disclosed |
| CN-117940414-A | Compounds for targeting IRAK4 protein degradation | 渤健马萨诸塞州股份有限公司 | 2024-04-26 | — | — | CN | disclosed |
| CN-117658877-A | Shulin acid intermediate impurity and preparation method thereof | 宁波大红鹰药业股份有限公司 | 2024-03-08 | — | — | CN | disclosed |
| US-4577040-A | Method for preparing diorganopolysiloxanes containing fluoroalkyl groups | WACKER-CHEMIE GMBH (DE) | 1986-03-18 | — | — | US | disclosed |
| US-4413006-A | N-Aryl-N-phenoxy-alkyl-piperazine compounds useful in decreasing intracranial pressure | TANABE SEIYAKU CO., LTD. (JP) | 1983-11-01 | — | — | US | disclosed |
| EP-0034284-B1 | PIPERAZINE DERIVATIVE, PROCESSES FOR PREPARING THE SAME AND THERAPEUTIC COMPOSITIONS CONTAINING IT | Tanabe Seiyaku Co., Ltd. (JP) | 1983-10-05 | — | — | EP | disclosed |
| EP-0034752-B1 | PHENOXYALKANE DERIVATIVE AND PROCESSES FOR PREPARING SAME | Tanabe Seiyaku Co., Ltd. (JP) | 1983-06-08 | — | — | EP | disclosed |
| EP-0034752-A1 | Phenoxyalkane derivative and processes for preparing same | Tanabe Seiyaku Co., Ltd. (JP) | 1981-09-02 | — | — | EP | disclosed |
| EP-0034284-A2 | Piperazine derivative, processes for preparing the same and therapeutic compositions containing it | Tanabe Seiyaku Co., Ltd. (JP) | 1981-08-26 | — | — | EP | disclosed |