Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.31 |
| ▸ | HPGD | P15428 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL127356 | 0.74 | KDM4E (0.37) | MAPTCYP2C9CYP2C19HIF1ACYP3A4 | |
| SCHEMBL29378184 | 0.74 | KDM4E (0.37) | MAPTCYP2C9CYP2C19HIF1ACYP3A4 | |
| SCHEMBL10758352 | 0.74 | ACHE (0.46) | MAPTTP53CYP2C9CYP2C19HIF1A | |
| SCHEMBL4867080 | 0.74 | KDM4E (0.37) | MAPTCYP2C9CYP2C19HIF1ACYP3A4 | |
| SCHEMBL11292394 | 0.73 | CYP3A4 (0.48) | SMN1; SMN2MAPTCYP3A4ALDH1A1CHRM1 | |
| Bromide SCHEMBL7236796 | 0.72 | KDM4E (0.36) | MAPTALDH1A1ACHEGAALMNA | |
| SCHEMBL19047158 | 0.70 | ALDH1A1 (0.39) | SMN1; SMN2MAPTTP53HIF1ACYP3A4 | |
| SCHEMBL2568645 | 0.68 | ACHE (0.40) | SMN1; SMN2MAPTCYP3A4ALDH1A1CHRM1 | |
| SCHEMBL26287618 | 0.68 | ACHE (0.40) | SMN1; SMN2MAPTCYP3A4ALDH1A1GPR35 | |
| SCHEMBL28291367 | 0.68 | GABRA1 (0.36) | SMN1; SMN2ALDH1A1ALOX15POLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1420019-B1 | Substituted pyridino pentaazamacrocyle ligands | MONSANTO CO (US) | 2007-07-25 | — | — | EP | disclosed |
| EP-1420022-B1 | Use of substituted pyridino pentaazamacrocyle complexes having superoxide dismutase activity | MONSANTO CO (US) | 2007-07-04 | — | — | EP | disclosed |
| EP-1212323-B1 | SUBSTITUTED PYRIDINO PENTAAZAMACROCYLE COMPLEXES HAVING SUPEROXIDE DISMUTASE ACTIVITY | MONSANTO CO (US) | 2004-06-09 | — | — | EP | disclosed |
| EP-1420022-A1 | Substituted pyridino pentaazamacrocyle complexes having superoxide dismutase activity | MONSANTO COMPANY (US) | 2004-05-19 | — | — | EP | disclosed |
| EP-1420019-A1 | Substituted pyridino pentaazamacrocyle ligands having superoxide dismutase activity | MONSANTO COMPANY (US) | 2004-05-19 | — | — | EP | disclosed |
| WO-2001019823-A9 | SUBSTITUTED PYRIDINO PENTAAZAMACROCYLE COMPLEXES HAVING SUPEROXIDE DISMUTASE ACTIVITY | MONSANTO CO (US) | 2002-09-26 | — | — | WO | disclosed |
| EP-1212323-A2 | SUBSTITUTED PYRIDINO PENTAAZAMACROCYLE COMPLEXES HAVING SUPEROXIDE DISMUTASE ACTIVITY | MONSANTO COMPANY (US) | 2002-06-12 | — | — | EP | disclosed |
| US-6214817-B1 | NITROGEN MACROCYCLE COMPLEXES WITH MANGANESE AND IRON | MONSANTO COMPANY | 2001-04-10 | — | — | US | disclosed |
| WO-2001019823-A2 | SUBSTITUTED PYRIDINO PENTAAZAMACROCYLE COMPLEXES HAVING SUPEROXIDE DISMUTASE ACTIVITY | MONSANTO COMPANY (US) | 2001-03-22 | — | — | WO | disclosed |