Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.30 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL4481198 | 0.99 | KDR (0.31) | KDR | |
| SCHEMBL4463819 | 0.81 | HSD11B1 (0.38) | — | |
| Bromide SCHEMBL4466117 | 0.81 | HSD11B1 (0.37) | — | |
| SCHEMBL5218539 | 0.80 | CYP11B1 (0.36) | KDM4C | |
| SCHEMBL4465415 | 0.79 | NPC1 (0.36) | — | |
| SCHEMBL1483281 | 0.79 | — | — | |
| Bromide SCHEMBL4467487 | 0.79 | CYP11B1 (0.36) | — | |
| SCHEMBL4465250 | 0.78 | KDM1A (0.40) | — | |
| SCHEMBL4470038 | 0.78 | HPGDS (0.39) | — | |
| SCHEMBL4463770 | 0.78 | ALOX5AP (0.34) | CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1465893-B1 | DERIVATIVES OF 5-(PYRIDIN-3-YL)-1-AZABICYCLO (3.2.1) OCTANE, THE PREPARATION THEREOF AND THE APPLICATION OF SAME IN THERAPEUTICS | SANOFI AVENTIS (FR) | 2007-02-28 | — | — | EP | claimed |