Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMARCA2 | P51531 | 2/20 | 0.31 |
| ▸ | PBRM1 | Q86U86 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.31 |
| ▸ | FYN | P06241 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.31 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 2/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL4467487 | 0.99 | CYP11B1 (0.36) | CYP11B1CYP11B2ADORA2AADORA1MAPK1 | |
| SCHEMBL4463632 | 0.83 | CYP11B1 (0.41) | CYP11B1ALDH1A1KDM4ESMN1; SMN2RAB9A | |
| SCHEMBL4463819 | 0.82 | HSD11B1 (0.38) | CYP11B1CYP11B2 | |
| SCHEMBL4463636 | 0.80 | — | — | |
| SCHEMBL4465415 | 0.80 | NPC1 (0.36) | CYP11B1CYP11B2NPC1 | |
| SCHEMBL5215973 | 0.80 | KDR (0.31) | KDM4C | |
| SCHEMBL5220760 | 0.80 | CYP11B1 (0.36) | CYP11B1CYP11B2ALDH1A1FYNMEN1 | |
| Bromide SCHEMBL4481198 | 0.79 | KDR (0.31) | — | |
| SCHEMBL5217300 | 0.79 | HPGDS (0.37) | CYP11B1CYP11B2ALDH1A1KDM4EFYN | |
| SCHEMBL4475112 | 0.78 | CHRNA7 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1465893-B1 | DERIVATIVES OF 5-(PYRIDIN-3-YL)-1-AZABICYCLO (3.2.1) OCTANE, THE PREPARATION THEREOF AND THE APPLICATION OF SAME IN THERAPEUTICS | SANOFI AVENTIS (FR) | 2007-02-28 | — | — | EP | claimed |