Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 1/20 | 0.47 |
| ▸ | ABCC9 | O60706 | 6/20 | 0.44 |
| ▸ | ABCC8 | Q09428 | 6/20 | 0.44 |
| ▸ | KCNJ11 | Q14654 | 6/20 | 0.44 |
| ▸ | KCNJ8 | Q15842 | 6/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5216594 | 1.00 | CYP11B2 (0.47) | CYP11B2ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL4681996 | 0.88 | ABCC9 (0.58) | CYP11B2ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL4681997 | 0.88 | ABCC9 (0.58) | CYP11B2ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL4679937 | 0.79 | ABCC9 (0.49) | CYP11B2ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL4679949 | 0.79 | ABCC9 (0.49) | CYP11B2ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL5216591 | 0.77 | ABCC9 (0.42) | ABCC9ABCC8KCNJ11KCNJ8POLB | |
| SCHEMBL4683396 | 0.75 | ABCC9 (0.68) | CYP11B2ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL4683403 | 0.75 | ABCC9 (0.68) | CYP11B2ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL4685649 | 0.74 | ABCC9 (0.65) | CYP11B2ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL4685640 | 0.74 | ABCC9 (0.65) | CYP11B2ABCC9ABCC8KCNJ11KCNJ8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1198456-B1 | POTASSIUM CHANNEL OPENERS | ABBOTT LAB (US) | 2007-09-19 | — | — | EP | disclosed |