Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 5/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5216952 | 0.70 | HPGD (0.57) | APEX1KMT2AKDM4EALDH1A1GLA | |
| SCHEMBL4919055 | 0.69 | MAPT (0.41) | POLBAPEX1MAPTMEN1KMT2A | |
| SCHEMBL1423962 | 0.65 | RAB9A (0.42) | POLBAPEX1MAPTMEN1KMT2A | |
| SCHEMBL25071114 | 0.65 | POLB (0.47) | POLBAPEX1MAPTKDM4E | |
| SCHEMBL28577924 | 0.65 | LMNA (0.56) | POLBMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL14721532 | 0.63 | POLB (0.39) | POLBAPEX1MAPTMEN1KMT2A | |
| SCHEMBL6748722 | 0.63 | MAPT (0.61) | POLBAPEX1MAPTMEN1KMT2A | |
| SCHEMBL13669850 | 0.62 | MAPT (0.51) | POLBMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6415026 | 0.62 | HCAR2 (0.52) | POLBMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL31175073 | 0.60 | POLB (0.46) | POLBAPEX1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1763303-A1 | SUBSTITUTED PYRIDAZINE CARBOXAMIDES AND DERIVATIVES THEREOF | Bayer CropScience Aktiengesellschaft (DE) | 2007-03-21 | — | — | EP | disclosed |
| WO-2006000333-A1 | SUBSTITUTED PYRIDAZINE CARBOXAMIDES AND DERIVATIVES THEREOF | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2006-01-05 | — | — | WO | disclosed |