Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3576946 | 0.82 | DGAT1 (0.48) | DGAT1TSHRELANE | |
| SCHEMBL10567903 | 0.81 | MEN1 (0.35) | — | |
| SCHEMBL4463447 | 0.80 | DGAT1 (0.46) | DGAT1TSHRELANE | |
| SCHEMBL3646518 | 0.77 | DGAT1 (0.43) | DGAT1 | |
| SCHEMBL10569449 | 0.75 | TRPA1 (0.35) | TSHR | |
| SCHEMBL4463173 | 0.75 | DGAT1 (0.50) | DGAT1TSHRELANE | |
| SCHEMBL16671511 | 0.74 | FAAH (0.52) | TSHR | |
| SCHEMBL2313446 | 0.73 | DGAT1 (0.48) | DGAT1TSHRELANE | |
| SCHEMBL808799 | 0.72 | DGAT1 (0.74) | DGAT1TSHRELANE | |
| SCHEMBL7753978 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1480640-B1 | PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | LILLY CO ELI (US) | 2007-08-15 | — | — | EP | disclosed |