Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 3/20 | 0.40 |
| ▸ | NOS2 | P35228 | 3/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 5/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.33 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4142328 | 1.00 | NOS3 (0.40) | NOS3NOS2TAAR1NPC1RAB9A | |
| SCHEMBL14457975 | 0.96 | NOS3 (0.37) | NOS3NOS2TAAR1NPC1RAB9A | |
| SCHEMBL14457936 | 0.86 | NOS3 (0.50) | NOS3NOS2TAAR1KIF11MAPT | |
| SCHEMBL14588923 | 0.85 | KDM1A (0.33) | NOS3NOS2KDM1AMAOBPTGES | |
| SCHEMBL14540777 | 0.85 | NOS3 (0.40) | NOS3NOS2TAAR1KIF11MAOB | |
| SCHEMBL6843372 | 0.85 | NOS3 (0.40) | NOS3NOS2TAAR1NPC1RAB9A | |
| SCHEMBL14540973 | 0.85 | NOS3 (0.40) | NOS3NOS2KIF11NOS1 | |
| SCHEMBL7043206 | 0.85 | NOS3 (0.40) | NOS3NOS2KIF11MAOBNOS1 | |
| SCHEMBL14063637 | 0.85 | NOS3 (0.40) | NOS3NOS2TAAR1KIF11MAOB | |
| SCHEMBL14588993 | 0.84 | NOS3 (0.34) | NOS3NOS2NPC1RAB9ANFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1429607-B1 | DELTA 1-PYRROLINES USED AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2007-04-04 | — | — | EP | disclosed |
| US-7179806-B2 | Δ1-pyrrolines used as pesticides | BAYER CROPSCIENCE AG (DE) | 2007-02-20 | — | — | US | disclosed |
| US-7179806-B2 | Δ1-pyrrolines used as pesticides | BAYER CROPSCIENCE AG (DE) | 2007-02-20 | — | — | US | disclosed |
| US-7179806-B2 | Δ1-pyrrolines used as pesticides | BAYER CROPSCIENCE AG (DE) | 2007-02-20 | — | — | US | disclosed |
| EP-1448549-B1 | DELTA1-PYRROLINES | BAYER CROPSCIENCE AG (DE) | 2006-11-15 | — | — | EP | disclosed |
| US-7115603-B2 | A1-pyrrolines | BAYER CROPSCIENCE AG (DE) | 2006-10-03 | — | — | US | disclosed |
| US-7074785-B2 | Δ1-pyrrolines used as pesticides | BAYER CROPSCIENCE AG (DE) | 2006-07-11 | — | — | US | disclosed |
| US-20060142369-A1 | Delta 1-pyrrolines used as pesticides | SEITZ THOMAS | 2006-06-29 | — | — | US | disclosed |
| US-20050228028-A1 | A1-pyrrolines | BAYER CROPSCIENCE AG (DE) | 2005-10-13 | — | — | US | disclosed |
| EP-1347957-B1 | DELTA 1-PYRROLINES USED AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2005-09-07 | — | — | EP | disclosed |
| WO-2003064386-A1 | DELTA1-PYRROLINES FOR USE AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2003-08-07 | — | — | WO | disclosed |
| EP-1322605-A1 | METHOD FOR PRODUCING DELTA 1-PYRROLINES | Bayer CropScience AG (DE) | 2003-07-02 | — | — | EP | disclosed |
| EP-1322606-A1 | METHOD FOR PRODUCING DELTA 1 -PYRROLINES | Bayer CropScience AG (DE) | 2003-07-02 | — | — | EP | disclosed |
| WO-2003040132-A1 | Δ1-PYRROLINES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2003-05-15 | — | — | WO | disclosed |
| WO-2003040130-A1 | $g(D)1-PYRROLINES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2003-05-15 | — | — | WO | disclosed |
| WO-2003040092-A2 | $g(D)1-PYRROLINES | BAYER AKTIENGESELLSCHAFT (DE) | 2003-05-15 | — | — | WO | disclosed |
| WO-2002081489-A1 | PALLADIUM-COMPLEXES BASED ON PYRROLINE-METAL COMPLEXES | BAYER CROPSCIENCE AG (DE) | 2002-10-17 | — | — | WO | disclosed |
| WO-2002046151-A1 | DELTA 1-PYRROLINES USED AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2002-06-13 | — | — | WO | disclosed |
| WO-2002024642-A1 | METHOD FOR PRODUCING Δ1-PYRROLINES | BAYER CROPSCIENCE AG (DE) | 2002-03-28 | — | — | WO | disclosed |
| WO-2002024645-A1 | METHOD FOR PRODUCING DELTA 1-PYRROLINES | BAYER CROPSCIENCE AG (DE) | 2002-03-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060142369-A1 | Delta 1-pyrrolines used as pesticides | DDT, CHRM1, OPRD1 | NOS3 792/4885NOS2 1085/4885TAAR1 215/4885 |
| US-20050228028-A1 | A1-pyrrolines | CHRM1, CYC1, DDT | NOS3 1244/4885NOS2 1219/4885TAAR1 101/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.