Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.38 |
| ▸ | BTK | Q06187 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5214586 | 0.85 | ALDH1A1 (0.39) | MAPTALDH1A1HPGDCNR1NPC1 | |
| SCHEMBL6105851 | 0.79 | MAPT (0.42) | MAPTALDH1A1HPGDCNR1NPC1 | |
| SCHEMBL5216599 | 0.77 | GABRP (0.43) | MAPTALDH1A1NPC1 | |
| SCHEMBL5214934 | 0.76 | EIF2AK2 (0.51) | CREBBP | |
| SCHEMBL6104272 | 0.74 | PIM1 (0.40) | MAPTALDH1A1HPGDCNR1NPC1 | |
| SCHEMBL6822005 | 0.72 | EGFR (0.45) | MAPT | |
| SCHEMBL5725747 | 0.70 | EIF2AK2 (0.48) | CREBBP | |
| SCHEMBL9911891 | 0.68 | SMN1; SMN2 (0.45) | MAPTALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL5220849 | 0.66 | EIF2AK2 (0.50) | CREBBP | |
| SCHEMBL5459554 | 0.66 | ALOX5 (0.42) | MAPTALDH1A1CNR1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1423389-B1 | PYRAZOLO-PYRIDINES FOR THE TREATMENT OF HERPES INFECTIONS | SMITHKLINE BEECHAM CORP (US) | 2007-06-06 | — | — | EP | disclosed |