Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 13/20 | 0.41 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | PAK1 | Q13153 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5220463 | 0.83 | KIT (0.45) | SCN10ATRPV1 | |
| SCHEMBL3296116 | 0.81 | TRPV1 (0.41) | SCN10ATRPV1RPS6KB1PAK1 | |
| SCHEMBL5222145 | 0.81 | P2RY12 (0.42) | TRPV1CNR1CNR2 | |
| SCHEMBL3453077 | 0.78 | ADRB1 (0.48) | SCN10A | |
| SCHEMBL27863228 | 0.76 | TP53 (0.41) | SCN10ATRPV1 | |
| SCHEMBL5219893 | 0.76 | DRD2 (0.56) | — | |
| SCHEMBL2071362 | 0.75 | HPGDS (0.62) | TRPV1RPS6KB1PAK1 | |
| SCHEMBL2328007 | 0.75 | ADRB1 (0.54) | — | |
| SCHEMBL27863224 | 0.74 | TRPV1 (0.39) | SCN10ATRPV1 | |
| SCHEMBL3453625 | 0.73 | KMT2A (0.43) | SCN10ATRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1664025-B1 | PYRROL DERIVATIVES WITH ANTIBACTERIAL ACTIVITY | ASTRAZENECA AB (SE) | 2007-09-19 | — | — | EP | disclosed |