SCHEMBL521935

SCHEMBL521935

Cc1[c]nc2ccccc2c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NQO2 P16083 4/20 0.46
MAPT P10636 4/20 0.46
ALDH1A1 P00352 3/20 0.46
HPGD P15428 2/20 0.46
GLA P06280 1/20 0.46
ACHE P22303 1/20 0.46
CYP1A2 P05177 4/20 0.45
KDM4E B2RXH2 3/20 0.44
STAT3 P40763 2/20 0.44
TDP1 Q9NUW8 1/20 0.44
GAA P10253 1/20 0.44
PDE10A Q9Y233 1/20 0.41
HTT P42858 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
MEN1 O00255 2/20 0.37
NPC1 O15118 2/20 0.37
KMT2A Q03164 2/20 0.37
MBNL1 Q9NR56 1/20 0.37
RAB9A P51151 1/20 0.37
USP2 O75604 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4723728 0.75 NCF1 (0.44) NQO2MAPTALDH1A1HPGDGLA
SCHEMBL584784 0.74 ALDH1A1 (0.46) NQO2MAPTALDH1A1HPGDGLA
SCHEMBL7060124 0.74 ALDH1A1 (0.46) NQO2MAPTALDH1A1HPGDGLA
SCHEMBL269884 0.74 ALDH1A1 (0.46) NQO2MAPTALDH1A1HPGDGLA
SCHEMBL558480 0.74 ALDH1A1 (0.46) NQO2MAPTALDH1A1HPGDGLA
SCHEMBL641339 0.74 ALDH1A1 (0.47) NQO2MAPTALDH1A1HPGDGLA
SCHEMBL558535 0.74 ALDH1A1 (0.46) NQO2MAPTALDH1A1HPGDGLA
SCHEMBL4757300 0.74 KDM4E (0.48) MAPTALDH1A1HPGDGLAACHE
SCHEMBL252593 0.74 KDM4E (0.47) NQO2MAPTALDH1A1HPGDGLA
SCHEMBL3054178 0.74 ALDH1A1 (0.41) NQO2MAPTALDH1A1HPGDGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 839 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108997438-B Red phosphorescent compound and organic light emitting diode device using the same 浙江华显光电科技有限公司 2023-10-27 CN claimed
CN-108997437-B Red phosphorescent compound and organic light emitting diode device using the same 浙江华显光电科技有限公司 2023-10-20 CN claimed
CN-109810146-B Green phosphorescent compound and organic electroluminescent device using the same 浙江华显光电科技有限公司 2021-11-16 CN claimed
CN-109988193-B Green phosphorescent compound and organic electroluminescent device using the same 浙江华显光电科技有限公司 2021-11-16 CN claimed
US-10829466-B2 Stilbene derivative and preparation method thereof BEIJING INSTITUTE OF TECHNOLOGY (CN) 2020-11-10 US claimed
US-20200148662-A1 NOVEL STILBENE DERIVATIVE AND PREPARATION METHOD THEREOF BEIJING INSTITUTE OF TECHNOLOGY (CN) 2020-05-14 US claimed
CN-111116673-A Red phosphorescent compound and organic electroluminescent device using the same 浙江华显光电科技有限公司 2020-05-08 CN claimed
CN-110981913-A Green phosphorescent compound and organic electroluminescent device using the same 浙江华显光电科技有限公司 2020-04-10 CN claimed
CN-110964063-A Green phosphorescent compound and organic electroluminescent device using the same 浙江华显光电科技有限公司 2020-04-07 CN claimed
CN-110938097-A Green phosphorescent compound and organic electroluminescent device using the same 浙江华显光电科技有限公司 2020-03-31 CN claimed
US-20020032288-A1 Method for producing a polymer by coordination polymerization KABUSHIKI KAISHA TOYOTA CHUO KENKYUSHO (JP) 2002-03-14 US claimed
EP-0559046-B1 N-amidinopiperidinyl(3/4)- or N-amidino-1,4-Oxazinyl(2)-substituted sulfonamides, process for their preparation and use as thrombin inhibitors HOFFMANN LA ROCHE (CH) 2001-07-11 EP claimed
US-5578594-A ANTICOAGULANTS HOFFMANN-LA ROCHE INC. (US) 1996-11-26 US claimed
US-5476846-A Administering anti-thrombotic and anti-asthmatic agent LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) 1995-12-19 US claimed
US-5387709-A Bronchodilator agents, anticoagulants, vasodilation LIPHA LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) 1995-02-07 US claimed
US-5378711-A α-arylacrylates substituted by a heterocyclic radical, and fungicides which contain these compounds BASF AKTIENGESELLSCHAFT (DE) 1995-01-03 US claimed
US-5270308-A Hypotensives TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1993-12-14 US claimed
EP-0559046-A1 N-amidinopiperidinyl(3/4)- or N-amidino-1,4-Oxazinyl(2)-substituted sulfonamides, process for their preparation and use as thrombin inhibitors F.HOFFMANN-LA ROCHE & CO. AKTIENGESELLSCHAFT (CH) 1993-09-08 EP claimed
EP-0236163-B1 DERIVATIVES OF N-ALPHA-SUBSTITUTED N-ALPHA-ARYLSULFONYLAMINOACYL P-AMIDINOPHENYLALANINAMIDES, THEIR PREPARATION, THEIR USE AS MEDICAMENTS AND THEIR INTERMEDIATES SANOFI (FR) 1990-10-03 EP claimed
EP-0335636-A1 Antiviral compounds SYNPHAR LABORATORIES INC. (CA) 1989-10-04 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10829466-B2 Stilbene derivative and preparation method thereof STS, F12, GLB1 NQO2 2903/4885MAPT 3955/4885ALDH1A1 449/4885
US-20200148662-A1 NOVEL STILBENE DERIVATIVE AND PREPARATION METHOD THEREOF STS, F12, STK38L NQO2 3551/4885MAPT 3976/4885ALDH1A1 415/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.