Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.47 |
| ▸ | HPGD | P15428 | 5/20 | 0.47 |
| ▸ | GAA | P10253 | 5/20 | 0.47 |
| ▸ | GLA | P06280 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.47 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.44 |
| ▸ | HTR3A | P46098 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | NQO2 | P16083 | 2/20 | 0.41 |
| ▸ | CASP1 | P29466 | 2/20 | 0.41 |
| ▸ | CASP7 | P55210 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4723728 | 0.75 | NCF1 (0.44) | ALDH1A1KDM4EHPGDGAAGLA | |
| SCHEMBL628270 | 0.75 | ALDH1A1 (0.43) | ALDH1A1KDM4EHPGDGAAGLA | |
| SCHEMBL584784 | 0.74 | ALDH1A1 (0.46) | ALDH1A1KDM4EHPGDGAAGLA | |
| SCHEMBL269884 | 0.74 | ALDH1A1 (0.46) | ALDH1A1KDM4EHPGDGAAGLA | |
| SCHEMBL558535 | 0.74 | ALDH1A1 (0.46) | ALDH1A1KDM4EHPGDGAAGLA | |
| SCHEMBL558480 | 0.74 | ALDH1A1 (0.46) | ALDH1A1KDM4EHPGDGAAGLA | |
| SCHEMBL7060124 | 0.74 | ALDH1A1 (0.46) | ALDH1A1KDM4EHPGDGAAGLA | |
| SCHEMBL521935 | 0.74 | NQO2 (0.46) | ALDH1A1KDM4EHPGDGAAGLA | |
| SCHEMBL252593 | 0.74 | KDM4E (0.47) | ALDH1A1KDM4EHPGDGAAGLA | |
| SCHEMBL9637930 | 0.74 | ALDH1A1 (0.41) | ALDH1A1KDM4EHPGDGAAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9944656-B2 | Benzothiazole macrocycles as inhibitors of human immunodeficiency virus replication | VIIV Healthcare UK (No.5) Limited (GB) | 2018-04-17 | — | — | US | claimed |
| EP-3105236-B1 | BENZOTHIAZOLE MACROCYCLES AS INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | VIIV HEALTHCARE UK (NO 5) LTD (GB) | 2017-10-18 | — | — | EP | claimed |
| US-20170008912-A1 | BENZOTHIAZOLE MACROCYCLES AS INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | BRISTOL-MYERS SQUIBB COMPANY | 2017-01-12 | — | — | US | claimed |
| EP-3105236-A1 | BENZOTHIAZOLE MACROCYCLES AS INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | VIIV HEALTHCARE (NO.5) LIMITED (GB) | 2016-12-21 | — | — | EP | claimed |
| WO-2015123230-A1 | BENZOTHIAZOLE MACROCYCLES AS INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | BRISTOL-MYERS SQUIBB COMPANY (US) | 2015-08-20 | — | — | WO | claimed |
| US-20080081766-A1 | IMAGE-FORMING METHOD USING HEAT-SENSITIVE TRANSFER SYSTEM | FUJIFILM CORPORATION (JP) | 2008-04-03 | — | — | US | claimed |
| EP-1885875-A2 | LUMINOGENIC AND FLUOROGENIC COMPOUNDS AND METHODS TO DETECT MOLECULES OR CONDITIONS | PROMEGA CORPORATION (US) | 2008-02-13 | — | — | EP | claimed |
| US-20070015790-A1 | Luminogenic and fluorogenic compounds and methods to detect molecules or conditions | JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT | 2007-01-18 | — | — | US | claimed |
| WO-2006130551-A2 | LUMINOGENIC AND FLUOROGENIC COMPOUNDS AND METHODS TO DETECT MOLECULES OR CONDITIONS | PROMEGA CORPORATION (US) | 2006-12-07 | — | — | WO | claimed |
| EP-0216483-B2 | Thermal transfer printing | ZENECA LTD (GB) | 1995-11-02 | — | — | EP | claimed |
| EP-0399673-B1 | Thermal transfer printing | ZENECA LTD (GB) | 1994-09-07 | — | — | EP | claimed |
| US-5091360-A | Using black dye mixture | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-02-25 | — | — | US | claimed |
| EP-0399673-A1 | Thermal transfer printing | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-11-28 | — | — | EP | claimed |
| EP-0216483-B1 | THERMAL TRANSFER PRINTING | ZENECA LIMITED (GB) | 1990-04-11 | — | — | EP | claimed |
| EP-0216483-A1 | Thermal transfer printing | ZENECA LIMITED (GB) | 1987-04-01 | — | — | EP | claimed |
| CN-118103059-A | Self-assembled nanoparticles based on amphiphilic peptides | 巴林萨斯生物疗法北美公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-111527099-B | Selective inhibitors of protein arginine methyltransferase 5 (PRMT 5) | 普莱鲁德疗法有限公司 | 2024-03-22 | — | — | CN | disclosed |
| US-4764178-A | Thermal transfer printing: hetero-aromatic azo dye | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-08-16 | — | — | US | disclosed |
| US-4764178-A | Thermal transfer printing: hetero-aromatic azo dye | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-08-16 | — | — | US | disclosed |
| EP-0216483-A1 | Thermal transfer printing | ZENECA LIMITED (GB) | 1987-04-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170008912-A1 | BENZOTHIAZOLE MACROCYCLES AS INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | MAVS, SARS1, RPL5 | ALDH1A1 2881/4885KDM4E 1052/4885HPGD 1894/4885 |
| US-20070015790-A1 | Luminogenic and fluorogenic compounds and methods to detect molecules or conditions | GLB1, NOD1, PYCARD | ALDH1A1 1974/4885KDM4E 4682/4885HPGD 1093/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.