SCHEMBL521940

SCHEMBL521940

CCCCOC(=O)C1=CCC(=O)C=C1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 9/20 0.46
TSHR P16473 5/20 0.46
TDP1 Q9NUW8 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
LMNA P02545 3/20 0.44
CYP1A2 P05177 2/20 0.44
CYP2C19 P33261 2/20 0.44
MAPK1 P28482 2/20 0.44
CYP2D6 P10635 1/20 0.44
NR1H2 P55055 1/20 0.44
RNASEL Q05823 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
CYP3A4 P08684 2/20 0.43
CYP2C9 P11712 1/20 0.43
PDE4D Q08499 1/20 0.43
TP53 P04637 1/20 0.41
STS P08842 1/20 0.41
ALDH1A1 P00352 2/20 0.41
AKR1C4 P17516 1/20 0.41
AKR1C3 P42330 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9312179 0.94 ALDH1A1 (0.49) ESR1TSHRLMNAMAPK1CYP3A4
SCHEMBL659382 0.94 ALDH1A1 (0.49) ESR1TSHRLMNAMAPK1CYP3A4
SCHEMBL190524 0.94 ALDH1A1 (0.49) ESR1TSHRLMNAMAPK1CYP3A4
SCHEMBL47935 0.90 ALDH1A1 (0.43) ESR1TSHRTDP1L3MBTL1LMNA
SCHEMBL598039 0.89 ALDH1A1 (0.42) ESR1TSHRTDP1L3MBTL1LMNA
SCHEMBL3110549 0.87 SERPINE1 (0.37) TSHRTDP1
SCHEMBL19304541 0.79 PRSS1 (0.49) ESR1TSHRTDP1LMNAMAPK1
SCHEMBL1435298 0.78 ALDH1A1 (0.46) TSHRTDP1LMNASMN1; SMN2CYP3A4
SCHEMBL9400200 0.76 TSHR (0.47) ESR1TSHRTDP1L3MBTL1LMNA
SCHEMBL48012 0.74 LMNA (0.37) TSHRTDP1L3MBTL1LMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 392 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6313319-B1 SLURRYING; RECRYSTALLIZATION IN ETHANOL; SEPARATING SOLID; FOOD PRESERVATIVES, COAGULANTS, PH CONTROLLERS SHIMADZU CORPORATION (JP) 2001-11-06 US claimed
EP-1048665-A1 METHOD FOR PURIFYING LACTIDE AND LACTIDE FOR FOOD ADDITIVES SHIMADZU CORPORATION (JP) 2000-11-02 EP claimed
US-5300293-A Mixture of antigrowth agent and dextrin SUMITOMO CHEMICAL CO., LTD. (JP) 1994-04-05 US claimed
US-5096710-A Cockroaches, juvenile hormone or chitin synthesis inhibitor, dextrin, plant oil SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-03-17 US claimed
US-4985413-A Poison bait for control of noxious insects SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-01-15 US claimed
US-4834977-A Poison bait for control of noxious insects SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1989-05-30 US claimed
US-4598035-A LEUCO AND DISAZO DYES FUJI PHOTO FILM CO., LTD. (JP) 1986-07-01 US claimed
US-4533929-A ANIONIC SURFACTANTS AS ANTIFOGGING AGENTS; DIETHYLHEXYL SULFOSUCCINATE FUJI PHOTO FILM CO., LTD. (JP) 1985-08-06 US claimed
JP-58018312-A None JP disclosed
JP-8141580-A None JP disclosed
JP-5279247-A None JP disclosed
JP-63230608-A None JP disclosed
JP-8163983-A None JP disclosed
US-20240196898-A1 INSANITARY INSECT PEST CONTROL METHOD USING CONDENSED HETEROCYCLIC COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2024-06-20 US disclosed
US-4479138-A PHENYL BENZOIC ESTER TO INCREASE SENSITIVITY FUJI PHOTO FILM CO., LTD. (JP) 1984-10-23 US disclosed
US-4425161-A Thermochromic materials PILOT INK COMPANY, LTD., (JP) 1984-01-10 US disclosed
JP-S5818312-A ALMIGHTY AROMATIC ATTRACTANT FUNAKI DENKI SEISAKUSHO:KK 1983-02-02 JP disclosed
US-4279909-A Antiallergic method FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1981-07-21 US disclosed
US-3963832-A A POLYSACCHARIDE, HUMECTANT, ABRASIVES TEIJIN LIMITED (JA) 1976-06-15 US disclosed
US-3935307-A POLYSACCHARIDE TEIJIN LIMITED (JA) 1976-01-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240196898-A1 INSANITARY INSECT PEST CONTROL METHOD USING CONDENSED HETEROCYCLIC COMPOUND C1S, C1R, CTRC ESR1 4826/4885TSHR 1820/4885TDP1 4620/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.