SCHEMBL521971

SCHEMBL521971

FC(F)(F)c1cc(OBOc2cc(C(F)(F)F)cc(C(F)(F)F)c2)cc(C(F)(F)F)c1

nearest known ligand 0.40

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 3/20 0.40
CES2 O00748 1/20 0.39
SOD1 P00441 1/20 0.38
ADRB1 P08588 1/20 0.36
GPR84 Q9NQS5 1/20 0.33
TDO2 P48775 1/20 0.32
MAPT P10636 1/20 0.31
RAPGEF4 Q8WZA2 1/20 0.31
ITGB3 P05106 1/20 0.31
ITGAV P06756 1/20 0.31
RXRA P19793 1/20 0.31
RXRB P28702 1/20 0.31
RXRG P48443 1/20 0.31
ALDH1A1 P00352 1/20 0.31
TSHR P16473 1/20 0.31
TLR8 Q9NR97 1/20 0.30
AR P10275 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1128558 0.87 SCN9A (0.35) IDO1CES2SOD1RXRARXRB
SCHEMBL16193422 0.85 ALDH1A1 (0.44) CES2MAPTRXRARXRBRXRG
SCHEMBL2341199 0.85 RAPGEF4 (0.38) IDO1SOD1MAPTRAPGEF4
SCHEMBL16783567 0.85 PTGS1 (0.39) IDO1CES2SOD1
SCHEMBL4457498 0.81 CES2 (0.41) IDO1CES2SOD1GPR84MAPT
SCHEMBL28906423 0.79 IDO1 (0.34) IDO1SOD1RXRARXRBRXRG
SCHEMBL289310 0.78 TSHR (0.47) IDO1CES2ALDH1A1TSHR
SCHEMBL29868638 0.78 CES2 (0.39) IDO1CES2SOD1MAPTITGB3
SCHEMBL892616 0.76 CYP11B1 (0.36) TLR8
SCHEMBL204711 0.75 CA1 (0.47) IDO1CES2ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 199 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3599234-B1 STEREOSELECTIVE PROCESS BOEHRINGER INGELHEIM INT (DE) 2021-04-07 EP claimed
EP-3599234-A1 STEREOSELECTIVE PROCESS Boehringer Ingelheim International GmbH (DE) 2020-01-29 EP claimed
US-10189776-B2 Stereoselective process BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2019-01-29 US claimed
US-20180258031-A1 STEREOSELECTIVE PROCESS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2018-09-13 US claimed
EP-3350173-A1 STEREOSELECTIVE PROCESS Boehringer Ingelheim International GmbH (DE) 2018-07-25 EP claimed
EP-3149138-A1 WATER CLUSTER-DOMINANT BORONIC ACID ALKALI SURFACTANT COMPOSITIONS AND THEIR USE The Procter & Gamble Company (US) 2017-04-05 EP claimed
WO-2017046355-A1 STEREOSELECTIVE PROCESS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2017-03-23 WO claimed
WO-2015184209-A1 WATER CLUSTER-DOMINANT BORONIC ACID ALKALI SURFACTANT COMPOSITIONS AND THEIR USE THE PROCTER & GAMBLE COMPANY (US) 2015-12-03 WO claimed
US-20150344817-A1 WATER CLUSTER-DOMINANT BORONIC ACID ALKALI SURFACTANT COMPOSITIONS AND THEIR USE THE PROCTER & GAMBLE COMPANY 2015-12-03 US claimed
US-8921299-B2 Detergents having acceptable color THE PROCTER & GAMBLE COMPANY (US) 2014-12-30 US claimed
US-20120289707-A1 PROCESS FOR THE PREPARATION OF AMIDES SYNGENTA CROP PROTECTION, LLC (US) 2012-11-15 US claimed
EP-2280944-A1 PROCESS FOR THE PREPARATION OF AMIDES Syngenta Limited (GB) 2011-02-09 EP claimed
WO-2009138375-A1 PROCESS FOR THE PREPARATION OF AMIDES SYNGENTA LIMITED (GB) 2009-11-19 WO claimed
EP-4043500-B1 ETHYLENE·ALPHA-OLEFIN·NON-CONJUGATED POLYENE COPOLYMER, USE THEREOF, AND MANUFACTURING METHOD THEREOF MITSUI CHEMICALS INC (JP) 2025-08-13 EP disclosed
US-20250243307-A1 ETHYLENE/a-OLEFIN/5-VINYL-2-NORBORNENE COPOLYMER, COMPOSITION CONTAINING SAID COPOLYMER, AND CROSSLINKED BODY MITSUI CHEMICALS, INC. (JP) 2025-07-31 US disclosed
US-12319758-B2 Sterically hindered phosphino-urea supported nickel (II) or palladium (II) catalysts for the copolymerization of ethylene and polar comonomers DOW GLOBAL TECHNOLOGIES LLC (US) 2025-06-03 US disclosed
US-6403632-B1 CYCLIC AMIDE DERIVATIVE BRISTOL MYERS SQUIBB PHARMA CO (US) 2002-06-11 US disclosed
EP-1206265-A1 SRC KINASE INHIBITOR COMPOUNDS Merck & Co., Inc. (US) 2002-05-22 EP disclosed
WO-2001000213-A1 SRC KINASE INHIBITOR COMPOUNDS MERCK & CO., INC. (US) 2001-01-04 WO disclosed
US-6057336-A ANTIINFLAMMATORY AGENTS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2000-05-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12319758-B2 Sterically hindered phosphino-urea supported nickel (II) or palladium (II) catalysts for the copolymerization of ethylene and polar comonomers PCNA, NIT2, MCM7 IDO1 1175/4885CES2 1075/4885SOD1 40/4885
US-10189776-B2 Stereoselective process CYP4A11, CYP4B1, CYP3A4 IDO1 3137/4885CES2 491/4885SOD1 4243/4885
US-20120289707-A1 PROCESS FOR THE PREPARATION OF AMIDES CHRM2, CHRM1, CYP1B1 IDO1 638/4885CES2 220/4885SOD1 619/4885
US-20180258031-A1 STEREOSELECTIVE PROCESS CYP4A11, CYP4B1, CYP3A4 IDO1 3137/4885CES2 491/4885SOD1 4243/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.