Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.60 |
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
| ▸ | LDHA | P00338 | 1/20 | 0.55 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.50 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.48 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.45 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1727869 | 0.89 | KDM4E (0.62) | KDM4ERECQLLDHAMALT1HSD11B1 | |
| SCHEMBL3269140 | 0.84 | KDM4E (0.57) | KDM4ERECQLLDHACHRM4MALT1 | |
| SCHEMBL1730153 | 0.83 | CHRM4 (0.52) | CHRM4MALT1DRD2 | |
| SCHEMBL1730203 | 0.83 | CHRM4 (0.51) | CHRM4MALT1 | |
| SCHEMBL13622633 | 0.82 | KDM4E (0.66) | KDM4ERECQLLDHAMALT1HSD11B1 | |
| SCHEMBL5220690 | 0.80 | KDM4E (0.66) | KDM4ERECQLLDHAMALT1HSD11B1 | |
| SCHEMBL1728967 | 0.80 | NSD2 (0.47) | CHRM4DRD2 | |
| Trifluoroacetic Acid SCHEMBL1023728 | 0.79 | KDM4E (0.58) | KDM4ERECQLLDHAMALT1HSD11B1 | |
| SCHEMBL3110161 | 0.78 | KDM4E (0.79) | KDM4ERECQLLDHAMALT1HSD11B1 | |
| SCHEMBL1728813 | 0.77 | SIRT2 (0.51) | CHRM4MALT1DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |