Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5224286 | 0.95 | MAPK14 (0.51) | ALDH1A1KDM4E | |
| SCHEMBL3281794 | 0.87 | HPGDS (0.45) | HPGDS | |
| Hydrochloric Acid SCHEMBL3280894 | 0.87 | ALDH1A1 (0.51) | ALDH1A1HTR1AMAOAMAOBKCNH2 | |
| SCHEMBL3282345 | 0.86 | HPGDS (0.45) | HPGDSALDH1A1HTR1AMAOAMAOB | |
| SCHEMBL3289122 | 0.83 | MAPK14 (0.47) | — | |
| Hydrochloric Acid SCHEMBL3282645 | 0.82 | SMN1; SMN2 (0.49) | ALDH1A1KDM4E | |
| SCHEMBL3285361 | 0.82 | MAPK14 (0.46) | HPGDS | |
| SCHEMBL3281638 | 0.81 | ALDH1A1 (0.67) | ALDH1A1HTR1AMAOAMAOBKCNH2 | |
| SCHEMBL3281618 | 0.81 | LMNA (0.45) | ALDH1A1 | |
| SCHEMBL23608032 | 0.80 | KDM4E (0.47) | POLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1664025-B1 | PYRROL DERIVATIVES WITH ANTIBACTERIAL ACTIVITY | ASTRAZENECA AB (SE) | 2007-09-19 | — | — | EP | disclosed |