Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3C3 | Q8NEB9 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 5/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.31 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.31 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5221018 | 0.89 | MRGPRX4 (0.30) | MRGPRX4 | |
| SCHEMBL5223792 | 0.81 | KMT2A (0.37) | PIK3C3POLBTP53P2RX7 | |
| SCHEMBL5222900 | 0.77 | CTSD (0.37) | PIK3C3POLBTP53MAPT | |
| SCHEMBL5218901 | 0.74 | BACE1 (0.40) | POLBTP53 | |
| SCHEMBL5223174 | 0.71 | BACE1 (0.49) | PIK3C3POLBTP53MAPT | |
| SCHEMBL5220634 | 0.68 | BACE1 (0.52) | POLB | |
| SCHEMBL5219385 | 0.67 | POLB (0.39) | PIK3C3POLBTP53 | |
| SCHEMBL6828695 | 0.66 | POLB (0.47) | PIK3C3POLBTP53 | |
| SCHEMBL5221011 | 0.65 | CTSD (0.39) | PIK3C3POLBTP53MAPT | |
| SCHEMBL5218650 | 0.65 | POLB (0.44) | POLBTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567488-B1 | HYDROXYETHYLAMINE DERIVATIVES FOR THE TREATMENT OF ALZHEIMER'S DISEASE | GLAXO GROUP LTD (GB) | 2007-02-21 | — | — | EP | disclosed |