Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5221024 | 0.89 | PIK3C3 (0.35) | MRGPRX4 | |
| SCHEMBL5218910 | 0.74 | MCL1 (0.34) | — | |
| SCHEMBL5223182 | 0.71 | BACE1 (0.40) | — | |
| SCHEMBL5223792 | 0.69 | KMT2A (0.37) | — | |
| SCHEMBL5220629 | 0.68 | BACE1 (0.43) | — | |
| SCHEMBL5222900 | 0.68 | CTSD (0.37) | — | |
| SCHEMBL5218643 | 0.65 | DRD2 (0.35) | — | |
| SCHEMBL5218901 | 0.64 | BACE1 (0.40) | — | |
| SCHEMBL5219833 | 0.63 | BACE1 (0.41) | — | |
| SCHEMBL5223868 | 0.62 | CTSD (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567488-B1 | HYDROXYETHYLAMINE DERIVATIVES FOR THE TREATMENT OF ALZHEIMER'S DISEASE | GLAXO GROUP LTD (GB) | 2007-02-21 | — | — | EP | disclosed |