Hydrochloric Acid

Hydrochloric Acid

SCHEMBL5221036

C=CC(=O)NC(C)(C)CC(C)[N+](C)(C)C.[Cl-]

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
TSHR P16473 2/20 0.37
MAPK1 P28482 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
BBOX1 O75936 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27973107 0.98 ALDH1A1 (0.44) ALDH1A1CYP3A4CYP2C9CYP2C19MEN1
Iodide SCHEMBL11829332 0.97 ALDH1A1 (0.43) ALDH1A1CYP3A4CYP2C9CYP2C19MEN1
SCHEMBL1073217 0.80 ALDH1A1 (0.49) ALDH1A1CYP3A4CYP2C9CYP2C19MEN1
SCHEMBL1284022 0.79 ALDH1A1 (0.47) ALDH1A1CYP3A4CYP2C9CYP2C19MEN1
SCHEMBL9865067 0.77 ALDH1A1 (0.46) ALDH1A1CYP3A4CYP2C9CYP2C19MEN1
SCHEMBL23207822 0.76 TSHR (0.48) ALDH1A1CYP3A4CYP2C9CYP2C19MEN1
Hydrochloric Acid SCHEMBL9801852 0.76 ALDH1A1 (0.45) ALDH1A1CYP3A4CYP2C9CYP2C19MEN1
Hydrochloric Acid SCHEMBL1072129 0.75 ALDH1A1 (0.47) ALDH1A1CYP3A4CYP2C9CYP2C19MEN1
SCHEMBL5225500 0.75 ALDH1A1 (0.44) ALDH1A1CYP3A4CYP2C9CYP2C19MEN1
SCHEMBL27972962 0.75 TGFBR1 (0.33) BBOX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3707180-B1 WATER SOLUBLE COPOLYMERS WACKER CHEMIE AG (DE) 2021-05-05 EP claimed
US-20210108013-A1 WATER-SOLUBLE COPOLYMERS WACKER CHEMIE AG (DE) 2021-04-15 US claimed
US-9580591-B2 Use of hybrid copolymers as protective colloids for polymers WACKER CHEMIE AG (DE) 2017-02-28 US claimed
EP-2935142-B1 USE OF HYBRID COPOLYMERS AS PROTECTIVE COLLOIDS FOR POLYMERS WACKER CHEMIE AG (DE) 2016-10-12 EP claimed
EP-2935357-B1 USE OF POLYVINYL-ALCOHOL-STABILISED POLYMERISATES IN MINERAL CONSTRUCTION MATERIALS WACKER CHEMIE AG (DE) 2016-05-11 EP claimed
US-20150315374-A1 USE OF HYBRID COPOLYMERS AS PROTECTIVE COLLOIDS FOR POLYMERS WACKER CHEMIE AG (DE) 2015-11-05 US claimed
US-20150307684-A1 USE OF POLYVINYL-ALCOHOL-STABILISED POLYMERISATES IN MINERAL CONSTRUCTION MATERIALS WACKER CHEMIE AG (DE) 2015-10-29 US claimed
US-20210108013-A1 WATER-SOLUBLE COPOLYMERS WACKER CHEMIE AG (DE) 2021-04-15 US disclosed
US-9580591-B2 Use of hybrid copolymers as protective colloids for polymers WACKER CHEMIE AG (DE) 2017-02-28 US disclosed
US-9522986-B2 Mineral construction material based on polyvinyl-alcohol-stabilized polymerisates WACKER CHEMIE AG (DE) 2016-12-20 US disclosed
US-20150315374-A1 USE OF HYBRID COPOLYMERS AS PROTECTIVE COLLOIDS FOR POLYMERS WACKER CHEMIE AG (DE) 2015-11-05 US disclosed
US-20150307684-A1 USE OF POLYVINYL-ALCOHOL-STABILISED POLYMERISATES IN MINERAL CONSTRUCTION MATERIALS WACKER CHEMIE AG (DE) 2015-10-29 US disclosed
US-8193104-B2 Crosslinkable cationic emulsion binders and their use as a binder for nonwovens CELANESE INTERNATIONAL CORPORATION (US) 2012-06-05 US disclosed
EP-1448827-B1 CROSSLINKABLE CATIONIC EMULSION BINDERS AND THEIR USE AS A BINDER FOR NONWOVENS CELANESE INT CORP (US) 2007-09-05 EP disclosed
US-20050239356-A1 Crosslinkable cationic emulsion binders and their use as a binder for nonwovens NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) 2005-10-27 US disclosed
US-4308189-A ADDITION POLYMER POLYMERIZED IN PRESENCE OF CATIONIC GROUP-MODIFIED POLYVINYL ALCOHOL KURARAY COMPANY, LIMITED (JP) 1981-12-29 US disclosed