Succinic Acid

Succinic Acid

SCHEMBL5221290

C=CN.O=C(O)CCC(=O)O

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4

The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 known ✓ P23975 1/20 0.50
SLC6A4 known ✓ P31645 1/20 0.50
LMNA P02545 5/20 0.60
EGLN1 Q9GZT9 3/20 0.60
ALKBH5 Q6P6C2 1/20 0.60
SUCNR1 Q9BXA5 1/20 0.60
TSHR P16473 5/20 0.50
NFKB1 P19838 3/20 0.50
BLM P54132 2/20 0.50
KMT2A Q03164 2/20 0.50
CYP2D6 P10635 2/20 0.50
SLC6A3 Q01959 1/20 0.50
MEN1 O00255 1/20 0.50
CYP2C19 P33261 1/20 0.50
GABRR1 P24046 2/20 0.48
HDAC3 O15379 2/20 0.47
HDAC1 Q13547 2/20 0.47
HDAC2 Q92769 2/20 0.47
HDAC8 Q9BY41 2/20 0.47
FFAR3 O14843 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Succinic Acid SCHEMBL27599427 1.00 LMNA (0.60) LMNAEGLN1ALKBH5SUCNR1TSHR
Succinic Acid SCHEMBL2558308 0.97 LMNA (0.56) LMNAEGLN1ALKBH5SUCNR1TSHR
Butyric Acid SCHEMBL10443315 0.85
SCHEMBL28023071 0.85 TSHR (0.67) LMNATSHRNFKB1KMT2ASLC6A2
Succinic Acid SCHEMBL4061508 0.83 LMNA (0.64) LMNAEGLN1ALKBH5SUCNR1TSHR
Succinic Acid SCHEMBL8407034 0.83 LMNA (0.64) LMNAEGLN1ALKBH5SUCNR1TSHR
Succinic Acid SCHEMBL19411367 0.83 LMNA (0.64) LMNAEGLN1ALKBH5SUCNR1TSHR
Succinic Acid SCHEMBL28114499 0.83 LMNA (0.64) LMNAEGLN1ALKBH5SUCNR1TSHR
Succinic Acid SCHEMBL15877803 0.81 LMNA (0.53) LMNAEGLN1ALKBH5SUCNR1TSHR
Succinic Acid SCHEMBL28443304 0.81 TSHR (0.65) LMNAEGLN1ALKBH5SUCNR1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1669379-B1 3,5-DIMETHYL-1-ADAMANTYL-AMMONIUM POLYMERIC SALTS AND THE USE THEREOF IN THE FORM OF ANTIVIRAL AGENTS AKCIJU SABIEDRIBA OLAINFARM (LV) 2007-11-14 EP claimed
EP-1759703-A1 IMMUNISTIMULATIVE AND INTERFERONOGENOUS AGENT Akciju Sabiedriba "Olainfarm" (LV) 2007-03-07 EP claimed
EP-1669379-A1 3,5-DIMETHYL-1-ADAMANTYL-AMMONIUM POLYMERIC SALTS AND THE USE THEREOF IN THE FORM OF ANTIVIRAL AGENTS Akciju Sabiedriba "Olainfarm" (LV) 2006-06-14 EP claimed
CN-101274989-B Semi-conductor polyimide film NITTO DENKO CORP 2012-12-26 CN disclosed
EP-1669379-B1 3,5-DIMETHYL-1-ADAMANTYL-AMMONIUM POLYMERIC SALTS AND THE USE THEREOF IN THE FORM OF ANTIVIRAL AGENTS AKCIJU SABIEDRIBA OLAINFARM (LV) 2007-11-14 EP disclosed
EP-1759703-A4 IMMUNISTIMULATIVE AND INTERFERONOGENOUS AGENT AKCIJU SABIEDRIBA OLAINFARM (LV) 2007-08-01 EP disclosed
EP-1759703-A1 IMMUNISTIMULATIVE AND INTERFERONOGENOUS AGENT Akciju Sabiedriba "Olainfarm" (LV) 2007-03-07 EP disclosed
EP-1759703-A1 IMMUNISTIMULATIVE AND INTERFERONOGENOUS AGENT Akciju Sabiedriba "Olainfarm" (LV) 2007-03-07 EP disclosed
EP-1669379-A1 3,5-DIMETHYL-1-ADAMANTYL-AMMONIUM POLYMERIC SALTS AND THE USE THEREOF IN THE FORM OF ANTIVIRAL AGENTS Akciju Sabiedriba "Olainfarm" (LV) 2006-06-14 EP disclosed
EP-1669379-A1 3,5-DIMETHYL-1-ADAMANTYL-AMMONIUM POLYMERIC SALTS AND THE USE THEREOF IN THE FORM OF ANTIVIRAL AGENTS Akciju Sabiedriba "Olainfarm" (LV) 2006-06-14 EP disclosed
WO-2006011823-A1 IMMUNISTIMULATIVE AND INTERFERONOGENOUS AGENT AKCIJU SABIEDRIBA 'OLAINFARM' (LV) 2006-02-02 WO disclosed