Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5222506 | 0.81 | L3MBTL1 (0.43) | L3MBTL1RAB9AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL5928148 | 0.79 | ALDH1A1 (0.47) | L3MBTL1RAB9AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL5223185 | 0.76 | NPC1 (0.45) | L3MBTL1RAB9AALDH1A1NPC1POLB | |
| SCHEMBL5224688 | 0.76 | NPC1 (0.45) | L3MBTL1RAB9AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL5225893 | 0.76 | HRH3 (0.55) | L3MBTL1RAB9AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL5223287 | 0.73 | NPC1 (0.45) | L3MBTL1RAB9AALDH1A1LMNANPC1 | |
| SCHEMBL5226319 | 0.73 | NPC1 (0.46) | L3MBTL1RAB9AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL5226114 | 0.73 | NPC1 (0.49) | L3MBTL1RAB9AALDH1A1LMNANPC1 | |
| SCHEMBL16213758 | 0.72 | LMNA (0.51) | L3MBTL1ALDH1A1SMN1; SMN2LMNAPOLB | |
| SCHEMBL5224485 | 0.72 | NPC1 (0.46) | L3MBTL1RAB9AALDH1A1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1771449-A1 | HISTAMINE-3 RECEPTOR ANTAGONISTS | Pfizer Products Incorporated (US) | 2007-04-11 | — | — | EP | claimed |
| WO-2006011043-A1 | HISTAMINE-3 RECEPTOR ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2006-02-02 | — | — | WO | claimed |
| US-20060019998-A1 | Histamine-3 receptor antagonist | PFIZER INC | 2006-01-26 | — | — | US | claimed |
| US-20060019998-A1 | Histamine-3 receptor antagonist | PFIZER INC | 2006-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060019998-A1 | Histamine-3 receptor antagonist | HRH3, HRH4, HRH2 | L3MBTL1 4112/4885RAB9A 295/4885ALDH1A1 1183/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.