Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPY1R | P25929 | 1/20 | 0.47 |
| ▸ | NPY2R | P49146 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.44 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5223439 | 0.80 | MEN1 (0.52) | MEN1KMT2ALMNASMN1; SMN2USP2 | |
| SCHEMBL4857823 | 0.74 | ALDH1A1 (0.55) | MEN1KMT2ALMNASMN1; SMN2USP2 | |
| SCHEMBL4857993 | 0.73 | ALDH1A1 (0.54) | LMNAALDH1A1ABCB1 | |
| SCHEMBL5901643 | 0.73 | POLB (0.70) | MEN1KMT2ALMNASMN1; SMN2USP2 | |
| SCHEMBL5995987 | 0.73 | POLB (0.70) | MEN1KMT2ALMNASMN1; SMN2USP2 | |
| SCHEMBL4866968 | 0.72 | MEN1 (0.50) | MEN1KMT2ALMNASMN1; SMN2USP2 | |
| SCHEMBL5227165 | 0.72 | CACNA1G (0.57) | MEN1KMT2ALMNASMN1; SMN2USP2 | |
| SCHEMBL11372250 | 0.71 | MEN1 (0.55) | MEN1KMT2ALMNASMN1; SMN2USP2 | |
| SCHEMBL5221069 | 0.71 | MEN1 (0.49) | MEN1KMT2ALMNASMN1; SMN2USP2 | |
| SCHEMBL5228562 | 0.70 | CYP3A4 (0.48) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1806346-A1 | Substituted piperazine compounds and their use as fatty acid oxidation inhibitors | CV THERAPEUTICS, INC. (US) | 2007-07-11 | — | — | EP | disclosed |