Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | PKM | P14618 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5225953 | 0.81 | RAB9A (0.50) | RAB9ANPC1KMT2AMEN1HTT | |
| SCHEMBL5225357 | 0.75 | NPC1 (0.40) | RAB9ANPC1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL5223908 | 0.73 | ALDH1A1 (0.44) | RAB9ANPC1KMT2AMEN1HTT | |
| SCHEMBL10986929 | 0.72 | ALDH1A1 (0.71) | RAB9ANPC1KMT2AMEN1HTT | |
| SCHEMBL20982763 | 0.71 | ALDH1A1 (0.72) | RAB9ANPC1KMT2AMEN1HTT | |
| SCHEMBL5223899 | 0.69 | ALDH1A1 (0.45) | RAB9ANPC1KMT2AMEN1HTT | |
| SCHEMBL588563 | 0.68 | RAB9A (0.62) | RAB9ANPC1KMT2AMEN1HTT | |
| SCHEMBL4981850 | 0.68 | ALDH1A1 (0.51) | RAB9ANPC1KMT2AMEN1HTT | |
| Ammonia Solution, Strong SCHEMBL20358007 | 0.67 | RAB9A (0.60) | RAB9ANPC1KMT2AMEN1HTT | |
| SCHEMBL20982760 | 0.67 | ALDH1A1 (0.69) | RAB9ANPC1KMT2AMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1487824-B1 | DIAMINO-PYRIMIDINES AND THEIR USE AS ANGIOGENESIS INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2007-06-20 | — | — | EP | disclosed |