Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.44 |
| ▸ | LMNA | P02545 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5225943 | 0.84 | ALDH1A1 (0.49) | ALDH1A1KMT2ALMNAMAPTHTT | |
| SCHEMBL5225949 | 0.84 | ALDH1A1 (0.49) | ALDH1A1KMT2ALMNAMAPTHTT | |
| SCHEMBL5229039 | 0.78 | KMT2A (0.44) | ALDH1A1KMT2ALMNAMAPTHTT | |
| SCHEMBL5229049 | 0.78 | KMT2A (0.44) | ALDH1A1KMT2ALMNAMAPTHTT | |
| SCHEMBL4976760 | 0.78 | ALDH1A1 (0.44) | ALDH1A1KMT2ALMNAMAPTHTT | |
| SCHEMBL5226510 | 0.76 | MAPT (0.54) | ALDH1A1KMT2ALMNAMAPTHTT | |
| SCHEMBL5225363 | 0.74 | RAF1 (0.39) | MAPTKDM4ENPC1RAB9A | |
| SCHEMBL5223899 | 0.74 | ALDH1A1 (0.45) | ALDH1A1KMT2ALMNAMAPTHTT | |
| SCHEMBL5223905 | 0.73 | RAB9A (0.48) | ALDH1A1KMT2ALMNAMAPTHTT | |
| SCHEMBL4978681 | 0.73 | MAPT (0.41) | ALDH1A1KMT2ALMNAMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1487824-B1 | DIAMINO-PYRIMIDINES AND THEIR USE AS ANGIOGENESIS INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2007-06-20 | — | — | EP | disclosed |