Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.45 |
| ▸ | PKM | P14618 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5225953 | 0.78 | RAB9A (0.50) | ALDH1A1PKMRAB9ARXFP1KMT2A | |
| SCHEMBL10986929 | 0.75 | ALDH1A1 (0.71) | ALDH1A1PKMRAB9ARXFP1KMT2A | |
| SCHEMBL3194891 | 0.74 | ALDH1A1 (0.52) | ALDH1A1PKMRAB9ARXFP1KMT2A | |
| SCHEMBL5223908 | 0.74 | ALDH1A1 (0.44) | ALDH1A1PKMRAB9AKMT2ALMNA | |
| SCHEMBL5225347 | 0.74 | KDR (0.37) | ALDH1A1RAB9AKDM4EMAPTNPC1 | |
| SCHEMBL5225564 | 0.74 | KDR (0.38) | ALDH1A1KDM4ECYP2D6 | |
| SCHEMBL20982763 | 0.71 | ALDH1A1 (0.72) | ALDH1A1PKMRAB9ARXFP1KMT2A | |
| SCHEMBL5225949 | 0.71 | ALDH1A1 (0.49) | ALDH1A1PKMRAB9ARXFP1KMT2A | |
| SCHEMBL5225943 | 0.71 | ALDH1A1 (0.49) | ALDH1A1PKMRAB9ARXFP1KMT2A | |
| SCHEMBL1028889 | 0.70 | L3MBTL1 (0.49) | ALDH1A1LMNAMAPTHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1487824-B1 | DIAMINO-PYRIMIDINES AND THEIR USE AS ANGIOGENESIS INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2007-06-20 | — | — | EP | disclosed |