Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 2/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.30 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5227163 | 0.91 | POLB (0.31) | — | |
| SCHEMBL5228680 | 0.84 | PIK3CD (0.38) | — | |
| SCHEMBL5230676 | 0.81 | PIK3CD (0.36) | — | |
| SCHEMBL5224808 | 0.79 | MPO (0.37) | — | |
| SCHEMBL4772079 | 0.78 | NMT1 (0.36) | ADRA1DADRA1AADRA1B | |
| SCHEMBL5213315 | 0.72 | PDGFRA (0.33) | — | |
| SCHEMBL5225473 | 0.70 | METAP2 (0.38) | — | |
| SCHEMBL4938115 | 0.69 | EDNRA (0.38) | — | |
| SCHEMBL4770100 | 0.68 | DYRK1A (0.35) | — | |
| SCHEMBL9377138 | 0.67 | SENP5 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1636212-B1 | CYCLOALKYLSULFANYL SUBSTITUTED BENZO¬B|THIOPHENES AS THERAPEUTIC AGENTS | WARNER LAMBERT CO (US) | 2007-06-27 | — | — | EP | claimed |