Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS12 | P56730 | 12/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | OGG1 | O15527 | 1/20 | 0.55 |
| ▸ | F10 | P00742 | 4/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5224161 | 0.83 | PRSS12 (0.60) | PRSS12MAPTF10HDAC1HDAC8 | |
| SCHEMBL16210507 | 0.82 | F10 (0.70) | PRSS12MAPTOGG1F10HDAC1 | |
| SCHEMBL7249817 | 0.80 | F10 (0.51) | MAPTOGG1F10HDAC1HDAC8 | |
| SCHEMBL16562251 | 0.78 | MAPT (0.65) | PRSS12MAPTF10 | |
| SCHEMBL2248037 | 0.76 | F10 (0.69) | PRSS12MAPTOGG1F10HDAC1 | |
| SCHEMBL3774866 | 0.76 | MEN1 (0.63) | MAPTHDAC1HDAC8HDAC6 | |
| SCHEMBL4651922 | 0.75 | MAPT (0.78) | PRSS12MAPTF10 | |
| SCHEMBL6351071 | 0.74 | PRSS12 (0.69) | PRSS12F10 | |
| SCHEMBL6509362 | 0.74 | OGG1 (0.54) | PRSS12MAPTOGG1F10HDAC1 | |
| SCHEMBL7675240 | 0.73 | MCL1 (0.71) | MAPTOGG1HDAC1HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1014962-A4 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2007-06-27 | — | — | EP | disclosed |
| EP-1014962-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 2000-07-05 | — | — | EP | disclosed |
| WO-1999000121-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1999-01-07 | — | — | WO | disclosed |