Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 4/20 | 0.52 |
| ▸ | CNR1 | P21554 | 2/20 | 0.51 |
| ▸ | CNR2 | P34972 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | CASP7 | P55210 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | VNN1 | O95497 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5672664 | 0.91 | SLC22A12 (0.51) | SLC22A12CNR1CNR2MAPTSMN1; SMN2 | |
| SCHEMBL5227728 | 0.88 | SLC22A12 (0.54) | SLC22A12CNR1CNR2MAPTSMN1; SMN2 | |
| SCHEMBL5227553 | 0.87 | SLC22A12 (0.53) | SLC22A12MAPTCASP1CASP7CYP2C9 | |
| SCHEMBL5223239 | 0.83 | ESR1 (0.61) | — | |
| Hydrochloric Acid SCHEMBL5674613 | 0.83 | ABCB11 (0.62) | — | |
| SCHEMBL5672687 | 0.81 | SLC22A12 (0.52) | SLC22A12CNR1CNR2MAPTSMN1; SMN2 | |
| SCHEMBL7388946 | 0.81 | ANO1 (0.45) | SLC22A12CNR1CNR2MAPTSMN1; SMN2 | |
| SCHEMBL7392563 | 0.79 | MTNR1A (0.47) | SLC22A12CNR1CNR2MAPTSMN1; SMN2 | |
| SCHEMBL5671766 | 0.76 | ESR1 (0.62) | — | |
| Oxalic Acid SCHEMBL5673174 | 0.76 | ESR1 (0.59) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1315710-B1 | AMINOALKOXYBENZOYL-BENZOFURAN OR BENZOTHIOPHENE DERIVATIVES, METHOD FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAME | SANOFI AVENTIS (FR) | 2007-04-25 | — | — | EP | disclosed |