Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 7/20 | 0.53 |
| ▸ | EYA3 | Q99504 | 4/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | KMO | O15229 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5225465 | 0.87 | SLC22A12 (0.52) | SLC22A12EYA3CYP2C9LMNAKDM4E | |
| SCHEMBL5672687 | 0.87 | SLC22A12 (0.52) | SLC22A12EYA3PTPN1CYP2C9LMNA | |
| SCHEMBL5227159 | 0.85 | EYA3 (0.66) | SLC22A12EYA3PTPN1CYP2C9NR1H4 | |
| SCHEMBL16547889 | 0.81 | EYA3 (0.60) | SLC22A12EYA3PTPN1CYP2C9LMNA | |
| SCHEMBL5223239 | 0.79 | ESR1 (0.61) | — | |
| Hydrochloric Acid SCHEMBL5674613 | 0.79 | ABCB11 (0.62) | — | |
| SCHEMBL5672664 | 0.78 | SLC22A12 (0.51) | SLC22A12CYP2C9LMNAKDM4EALDH1A1 | |
| SCHEMBL7197250 | 0.76 | SLC22A12 (0.45) | SLC22A12EYA3PTPN1CYP2C9LMNA | |
| SCHEMBL5227728 | 0.74 | SLC22A12 (0.54) | SLC22A12EYA3PTPN1CYP2C9CASP1 | |
| SCHEMBL7385370 | 0.73 | ACP1 (0.42) | SLC22A12EYA3KMOFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1315710-B1 | AMINOALKOXYBENZOYL-BENZOFURAN OR BENZOTHIOPHENE DERIVATIVES, METHOD FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAME | SANOFI AVENTIS (FR) | 2007-04-25 | — | — | EP | disclosed |
| EP-1315710-A1 | AMINOALKOXYBENZOYL-BENZOFURAN OR BENZOTHIOPHENE DERIVATIVES, METHOD FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAME | SANOFI-SYNTHELABO (FR) | 2003-06-04 | — | — | EP | disclosed |
| WO-2002016340-A1 | AMINOALKOXYBENZOYL-BENZOFURAN OR BENZOTHIOPHENE DERIVATIVES, METHOD FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAME | SANOFI-SYNTHELABO (FR) | 2002-02-28 | — | — | WO | disclosed |