Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.45 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | PREP | P48147 | 1/20 | 0.44 |
| ▸ | FAP | Q12884 | 1/20 | 0.44 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.44 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.44 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3088285 | 0.84 | MCL1 (0.46) | ALDH1A1HPGD | |
| SCHEMBL5172182 | 0.84 | MCL1 (0.46) | ALDH1A1HPGD | |
| SCHEMBL440331 | 0.83 | KDM4E (0.45) | KDM4EHPGDTDP1GAADPP4 | |
| SCHEMBL4834357 | 0.82 | UCHL1 (0.49) | FKBP1AALDH1A1KDM4EPOLB | |
| SCHEMBL7592715 | 0.81 | ALDH1A1 (0.61) | FKBP1AALDH1A1TDP1CNR2HTT | |
| SCHEMBL3001673 | 0.79 | ALDH1A1 (0.49) | ALDH1A1DPP4 | |
| SCHEMBL20482097 | 0.79 | ALDH1A1 (0.49) | ALDH1A1DPP4 | |
| SCHEMBL20482428 | 0.79 | ALDH1A1 (0.49) | ALDH1A1DPP4 | |
| SCHEMBL4776003 | 0.77 | MGLL (0.48) | ALDH1A1 | |
| SCHEMBL2226530 | 0.77 | ALDH1A1 (0.66) | ALDH1A1DPP4PREPFAPDPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100430394-C | N- [ heteroaryl (piperidin-2-yl) methyl ] benzamide derivatives, their preparation and their therapeutic use | SANOFI AVENTIS (FR) | 2008-11-05 | — | — | CN | disclosed |
| EP-1680418-B1 | DERIVATIVES OF N-[HETEROARYL(PIPERIDINE-2-YL)METHYL]BENZAMIDE, PREPARATION METHOD THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI AVENTIS (FR) | 2007-05-09 | — | — | EP | disclosed |
| CN-1882581-A | N- [ heteroaryl (piperidin-2-yl) methyl ] benzamide derivatives, their preparation and their therapeutic use | SANOFI AVENTIS (FR) | 2006-12-20 | — | — | CN | disclosed |
| EP-1680418-A2 | DERIVATIVES OF N-[HETEROARYL(PIPERIDINE-2-YL)METHYL]BENZAMIDE, PREPARATION METHOD THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | Sanofi-Aventis (FR) | 2006-07-19 | — | — | EP | disclosed |
| WO-2005037781-A2 | DERIVATIVES OF N-[HETEROARYL(PIPERIDINE-2-YL)METHYL]BENZAMIDE, PREPARATION METHOD THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI-AVENTIS (FR) | 2005-04-28 | — | — | WO | disclosed |