Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 10/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 10/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.39 |
| ▸ | CCR3 | P51677 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2761178 | 0.89 | TSHR (0.48) | NPSR1ALDH1A1MEN1KMT2AHTT | |
| SCHEMBL5232268 | 0.87 | BCL2L11 (0.39) | ALDH1A1MEN1KMT2AKDM4EHTT | |
| SCHEMBL5224311 | 0.86 | LMNA (0.45) | ALDH1A1MEN1KMT2AHTTTSHR | |
| SCHEMBL5230462 | 0.86 | HTR1A (0.47) | ALDH1A1MEN1KMT2AKDM4EHTT | |
| SCHEMBL5228511 | 0.83 | MAPT (0.38) | ALDH1A1MEN1KMT2AKDM4EHTT | |
| SCHEMBL2761079 | 0.79 | TSHR (0.40) | NPSR1ALDH1A1MEN1KMT2AHTT | |
| SCHEMBL2761138 | 0.76 | LMNA (0.40) | NPSR1HTTLMNAUSP2MAPT | |
| SCHEMBL2761010 | 0.76 | MAPT (0.41) | NPSR1HTTLMNACHRM2CHRM1 | |
| SCHEMBL2761238 | 0.75 | LMNA (0.51) | NPSR1ALDH1A1MEN1KMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL1997591 | 0.74 | LMNA (0.50) | NPSR1ALDH1A1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1611122-B1 | SUBSTITUTED PYRAZOLE COMPOUNDS | MERCK PATENT GMBH (DE) | 2007-06-13 | — | — | EP | disclosed |