Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 1/20 | 0.51 |
| ▸ | ATRIP | Q8WXE1 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | PRKDC | P78527 | 6/20 | 0.47 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5227063 | 0.77 | RAB9A (0.63) | KDM4EALDH1A1TDP1HSD17B10TP53 | |
| SCHEMBL11751124 | 0.76 | TSHR (0.68) | KDM4EALDH1A1TDP1HSD17B10TSHR | |
| SCHEMBL9695305 | 0.75 | ALDH1A1 (0.52) | ATRATRIPKDM4EALDH1A1HSD17B10 | |
| SCHEMBL9695483 | 0.73 | ALDH1A1 (0.61) | KDM4EALDH1A1TDP1HSD17B10TSHR | |
| SCHEMBL11485058 | 0.72 | ATR (0.48) | ATRATRIPKDM4EALDH1A1TDP1 | |
| SCHEMBL11493246 | 0.71 | ATR (0.51) | ATRATRIPKDM4EALDH1A1TDP1 | |
| SCHEMBL28792675 | 0.70 | PRKDC (0.54) | KDM4EALDH1A1PRKDCPIK3CDPIK3CA | |
| SCHEMBL4880606 | 0.70 | KDM4E (0.70) | KDM4EALDH1A1TDP1HSD17B10TP53 | |
| SCHEMBL2208450 | 0.69 | AKR1C3 (0.68) | KDM4EALDH1A1HSD17B10TP53PRKDC | |
| SCHEMBL9548136 | 0.69 | KMT2A (0.74) | KDM4EALDH1A1PRKDCHPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1300399-B1 | PHENYLPYRIDAZINE DERIVATIVES AND DRUGS CONTAINING THE SAME | KOWA CO (JP) | 2007-08-22 | — | — | EP | disclosed |
| US-6664256-B1 | Interleukin- 1 beta inhibitors | KOWA CO., LTD. (JP) | 2003-12-16 | — | — | US | disclosed |
| EP-1300399-A1 | PHENYLPYRIDAZINE DERIVATIVES AND DRUGS CONTAINING THE SAME | Kowa Co., Ltd. (JP) | 2003-04-09 | — | — | EP | disclosed |