Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.63 |
| ▸ | NPC1 | O15118 | 8/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5224281 | 0.87 | PTGS2 (0.57) | RAB9ANPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL5223497 | 0.78 | SMN1; SMN2 (0.54) | ALDH1A1MAPTHPGDKDM4EGAA | |
| SCHEMBL5227038 | 0.77 | ATR (0.51) | RAB9ANPC1ALDH1A1MAPTHPGD | |
| SCHEMBL4580434 | 0.73 | CCNC (0.71) | RAB9ANPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL9548091 | 0.73 | ALDH1A1 (0.77) | RAB9ANPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL9792247 | 0.72 | HPGD (0.79) | RAB9AMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL16489344 | 0.71 | KMT2A (0.58) | RAB9ANPC1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL16470880 | 0.71 | KMT2A (0.57) | RAB9ANPC1MEN1KMT2A | |
| SCHEMBL18889284 | 0.69 | RIPK1 (0.75) | RAB9ANPC1MEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL5363354 | 0.68 | PTGS2 (0.60) | RAB9ANPC1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1300399-B1 | PHENYLPYRIDAZINE DERIVATIVES AND DRUGS CONTAINING THE SAME | KOWA CO (JP) | 2007-08-22 | — | — | EP | disclosed |
| US-6664256-B1 | Interleukin- 1 beta inhibitors | KOWA CO., LTD. (JP) | 2003-12-16 | — | — | US | disclosed |
| EP-1300399-A1 | PHENYLPYRIDAZINE DERIVATIVES AND DRUGS CONTAINING THE SAME | Kowa Co., Ltd. (JP) | 2003-04-09 | — | — | EP | disclosed |